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Effect of loading dose of magnesium sulfate on doppler parameters of the uterine , fetal umbilical and middle cerebral arteries in patients with severe preeclampsia and eclampsia /

Mahmoud Ahmed Ismael Abdelhameed

Effect of loading dose of magnesium sulfate on doppler parameters of the uterine , fetal umbilical and middle cerebral arteries in patients with severe preeclampsia and eclampsia / تأثر الجرعة التحميلية لسلفات الماغنسوم علي معايير دوبلر شراين الرحم و الحبل السري و الدماغ الاوسط للجنين في مريضات ما قبل الإكلامسيا الشديدة و الإكلامسيا Mahmoud Ahmed Ismael Abdelhameed ; Supervised Ahmed Lotfy Aboul Nasr , Ahmed Samy Aly , Mai Hamed Mohammed - Cairo : Mahmoud Ahmed Ismael Abdelhameed , 2016 - 126 P. : charts , facsimiles ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Gynaecology and Obstetrics

Objective : To evaluate the effect of loading dose of magnesium sulfate on Doppler velocimetry parameters (resistance index [RI], pulsatility index [PI] and systolic/diastolic [S/D] ratio) of the uterine , fetal umbilical and middle cerebral arteries in pregnant patients with severe preeclampsia and eclampsia and to assess serum magnesium level in those patients .Methods : A observational analytic case - control study that included sixty pregnant women who attended the Obstetrics and Gynaecology hospital , Kasr El Aini, Cairo university during the period from March 2015 till the end of January 2016 was developed . They were divided into two groups ; Study group & Control group. The Study group included 30 pregnant patients with severe preeclampsia or eclampsia who were given magnesium sulphate therapy . Doppler flow velocity parameters (resistance index [RI],pulsatility index [PI] and systolic/diastolic [S/D] ratio) were evaluated in the uterine, fetal umbilical and middle cerebral arteries before and 20 minutes after intravenous administration of 6 grams of magnesium sulfate ( Loading dose). Maternal parameters such as heart rate, systolic and diastolic blood pressures were recorded. Serum magnesium before and 20 minutes after administration of magnesium sulphate was measured



Doppler ultrasound Magnesium sulfate Preeclampsia