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Efficacy and safety of intravenous 3% hypertonic saline compared to Mannitol 20% for lowering intraocular pressure in glaucoma patients : A prospective randomized double blinded study /

Omnia Adel Mandor

Efficacy and safety of intravenous 3% hypertonic saline compared to Mannitol 20% for lowering intraocular pressure in glaucoma patients : A prospective randomized double blinded study / مدى فاعليه و سلامه استخدام محلول ملح بتركيز3% مقارنة باستخدام المانيتول 20% عن طريق التنقيط الوريدى بهدف تقليل ضغط العين فى مرضي المياه الزرقاء : دراسة مستقبليه عشوائيه مزدوجه التعميه Omnia Adel Mandor ; Supervised Mohammed Hafez Elsaied Hafez , Gihan Mohammed Obayah , Maha Mohammed Ismail Youssef - Cairo : Omnia Adel Mandor , 2016 - 72 P. : charts , facsimiles ; 25cm

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Anesthesia

The reduction of acutely raised intraocular pressure prior to surgery is often essential. Mannitol has been the primary hyperosmolar agent for nearly a century and remains the gold standard for medical management of intracranial hypertension. anaesthesiologists use intravenous hypertonic saline for lowering intracranial pressure and over the last 25 years, HTS has become a progressively more common alternative to mannitol.Well established systemic medications to reduce IOP rapidly include acetazolamide either oral or intravenous, oral glycerol and intravenous mannitol. Because of their contraindication profiles and dangerous side effects, they are not always applicable to all patients



Glaucoma patients Intravenous 3% Mannitol 20%