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A prospective cohort study on the predictive value of vascular calcification in detection of cardiovascular morbidity and mortality in end stage renal disease patients on regular hemodialysi /

Fadia Moris Bolis

A prospective cohort study on the predictive value of vascular calcification in detection of cardiovascular morbidity and mortality in end stage renal disease patients on regular hemodialysi / دراسة مستقبلية لمتابعة و توقع تأثير تكلس الأوعية الدموية على حدوث أمراض القلب و الأوعية الدموية و الوفيات فى مرضى الفشل الكلوى المزمن المعالج بالأستصفاء الدموى Fadia Moris Bolis ; Supervised Tarek Hussein Elshabony , Mohamed Nasr Allah , Amr Nassef - Cairo : Fadia Moris Bolis , 2016 - 161 P. : facsimiles ; 25cm

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Internal Medicine

Background and aims the incidence of cardiovascular disease among patients with end stage renal disease (ESRD) on regular hemodialysis was found to be 10-20 times higher than in the general population. Cardiovascular disease accounts for 50 % of all deaths in this population.Atherosclerosis is the most frequent cause of cardiovascular morbidity in patients with ESRD. Aim of study: 1-To detect the prevalence of vascular calcification among hemodialysis patients using different radiological scores. 2-To detect the association between mortality among hemodialysis patients and vascular calcification scores. Patients and Methods 92 patientson regular hemodialysisat Kasr Elaini hemodialysis unit and Kasr ElAini nephro-urology unit (king fahd unit) were only included 47 female, 45male.Included subjects were evaluated by: History taking,clinical examination and laboratory investigations.vascular calcification was assessed by non contrast ct abdomen, lateral lumbar x ray and xray of both hand and pelvis. Results In our study we found high prevalence of vascular calcification among patients on regular hemodialysis using 6 different radiological scores. Two of these scores utilized plain radiography while 4 scores utilized CT of thoracic and abdominal aorta. We demonstrated a correlation between the different scores despite the use of various techniques, and measuring calcification in different vascular territories. The prevalence of vascular calcification was significantly higher when measured by CT compared to plain X rays



Detection of cardiovascular morbidity Predictive value of vascular calcification Regular hemodialysi