N{u2160}-linked metatonin dimers as bivalent ligands targeting dimeric melatonin receptors /
Samy Abdalla Mehany Habib
N-linked metatonin dimers as bivalent ligands targeting dimeric melatonin receptors / كمركبات ثنائية التكافؤ تستهدف مستقبلات الميلاتونين المثنوية N- مركبات ميلاتونين ثنائية الوحدات مرتبطة عن طريق Samy Abdalla Mehany Habib ; Supervsied Darius P. Zlotos - Cairo : Samy Abdalla Mehany Habib , 2014 - 118 Leaves ; 30cm
Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceulical Chemistry
The diverse physiological actions of the pineal neurohormone melatonin are mainly mediated through activation of two G-protein-coupled receptors MT₁, and MT₂. These receptors are known to form homo-and heterodimers with distinct functions and properties opening new perspectives for drug design and drug treatment. The bivalent ligand approach is a common strategy for targeting dimeric GPCRs
Dimeric melatonin receptors N-linked metatonin dimers Targeting dimeric GPCRs
N-linked metatonin dimers as bivalent ligands targeting dimeric melatonin receptors / كمركبات ثنائية التكافؤ تستهدف مستقبلات الميلاتونين المثنوية N- مركبات ميلاتونين ثنائية الوحدات مرتبطة عن طريق Samy Abdalla Mehany Habib ; Supervsied Darius P. Zlotos - Cairo : Samy Abdalla Mehany Habib , 2014 - 118 Leaves ; 30cm
Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceulical Chemistry
The diverse physiological actions of the pineal neurohormone melatonin are mainly mediated through activation of two G-protein-coupled receptors MT₁, and MT₂. These receptors are known to form homo-and heterodimers with distinct functions and properties opening new perspectives for drug design and drug treatment. The bivalent ligand approach is a common strategy for targeting dimeric GPCRs
Dimeric melatonin receptors N-linked metatonin dimers Targeting dimeric GPCRs