Effect of SERCA gene modified stem cells on functional recovery of diabetic cardiomyopathy /
Yasmeen Safwat Salah Mohamed
Effect of SERCA gene modified stem cells on functional recovery of diabetic cardiomyopathy / جين على الانتعاش الوظيفى فى اعتلال عضلة القلب السكرى SERCA2a تأثير الخلايا الجذعية المعدلة بال Yasmeen Safwat Salah Mohamed ; Supervised Lobna Abdelaal Kassem , Maha Mohamed Gamal Eldin , Nadia Aziz Yassin - Cairo : Yasmeen Safwat Salah Mohamed , 2016 - 185 Leaves : charts , facsimiles , photographs ; 30cm
Thesis (Ph.D.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Molecular Physiology
Aims/hypothesis: This study addressed the potential application of genetically modified mesenchymal stem cells (MSCs) was sarcoplasmic reticulum Ca⁺² ATPase2a (SERCA2a) gene in the treatment of diabetic cardiomyopathy (DC) focusing on the role of (SERCA2a) in the pathogenesis of such dysfunction. Methods: 50 rats were divided into five groups: control, DC, DC treated with either MSCs or genetically modified MSCs (MSCs SERCA2a) injected in tail vein or MSCsSERCA2a and ascorbic acid A.A
Diabetic cardiomyopathy Genetically modified mesenchymal stem cells Mesenchymal stem cells
Effect of SERCA gene modified stem cells on functional recovery of diabetic cardiomyopathy / جين على الانتعاش الوظيفى فى اعتلال عضلة القلب السكرى SERCA2a تأثير الخلايا الجذعية المعدلة بال Yasmeen Safwat Salah Mohamed ; Supervised Lobna Abdelaal Kassem , Maha Mohamed Gamal Eldin , Nadia Aziz Yassin - Cairo : Yasmeen Safwat Salah Mohamed , 2016 - 185 Leaves : charts , facsimiles , photographs ; 30cm
Thesis (Ph.D.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Molecular Physiology
Aims/hypothesis: This study addressed the potential application of genetically modified mesenchymal stem cells (MSCs) was sarcoplasmic reticulum Ca⁺² ATPase2a (SERCA2a) gene in the treatment of diabetic cardiomyopathy (DC) focusing on the role of (SERCA2a) in the pathogenesis of such dysfunction. Methods: 50 rats were divided into five groups: control, DC, DC treated with either MSCs or genetically modified MSCs (MSCs SERCA2a) injected in tail vein or MSCsSERCA2a and ascorbic acid A.A
Diabetic cardiomyopathy Genetically modified mesenchymal stem cells Mesenchymal stem cells