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Influence of genetic variation in vitamin D-binding protein on circulating 25-hydroxyvitamin D levels, vitamin D binding protein levels, parathyroid hormone levels and susceptibility to cardiovascular disease /

Nada Khaled Sedky

Influence of genetic variation in vitamin D-binding protein on circulating 25-hydroxyvitamin D levels, vitamin D binding protein levels, parathyroid hormone levels and susceptibility to cardiovascular disease / Nada Khaled Sedky ; Supervised Mihamed Zakaria Gad - Cairo : Nada Khaled Sedky , 2015 - 94 Leaves : charts , facsimiles ; 30cm

Thesis (M.Sc.) - Garman University - Faculty of Postgraduate Studies and Scientific Research - Department of Biochemistry

Cardiovascular disease (CVD) remains a major public health burden in Egypt with high mortality rate. Emerging research has suggested an association between vitamin D insufficiency and cardiovascular disease as low serum 25-hydroxyvitamin D (25(OH)D) was associated with higher for CVD. Vitamin D binding protein (VDBP) is the main systemic transporter of vitamin D and its common genetic polymorphisms result in the expression of different proteins with different affinities for vitamin D.

Cardiovascular disease (CVD) Parathyroid hormone levels Vitamin D