Association of diabetes mellitus with coronary atherosclerotic plaque burden and morphology measured by multidetector computed coronary angiography /
Reem Mohamed Hamed Elshall
Association of diabetes mellitus with coronary atherosclerotic plaque burden and morphology measured by multidetector computed coronary angiography / قياس مدى ارتباط داء السكرى بالعبء الناتج عن اللويحة المتصلبة بالشرايين التاجية و شكلها باستخدام الاشعة المقطعية متعددة المقاطع للشرايين التاجية Reem Mohamed Hamed Elshall ; Supervised Noha Hossam Eldein Ibrahim Behaire , Hazem Hamed A. Elhafiz Soliman - Cairo : Reem Mohamed Hamed Elshall , 2017 - 103 P. : facsimiles ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Radio-diagnosis
Background: Coronary artery disease (CAD) is a leading cause of morbidity and mortality in patients with diabetes mellitus (DM). Diabetics have more prevalent, extensive coronary atherosclerosis than non-diabetics, with an accelerated progression and higher prevalence of multi-vessel disease. Diabetics have also a higher prevalence of silent atherosclerotic lesions and asymptomatic ischemia, making the diagnosis of CAD easier to miss and allowing the disease to progress to an advanced stage before becoming clinically evident. Objectives: To identify the features of CAD in diabetic patients using coronary CT angiography (CCTA). Conclusion: Diabetes is an independent predictor of CAD and is also associated with more advanced CAD, evaluated by indexes of coronary atherosclerotic burden. The comprehensive information regarding the presence, severity and type of plaque noninvasively provided by CCTA, has made possible a detailed characterization of the coronary disease pattern of diabetic patients at an earlier stage of disease. Diabetics have a significantly higher prevalence of plaques in every anatomical subset (number of vessel and either proximal or distal localizations) and for the different plaque composition (higher prevalence of mixed plaque). Since mixed plaque is associated with worse long-term clinical outcomes, these findings support more aggressive preventive measures in this population
Atherosclerotic burden Coronary atherosclerotic plaque (CAP) Diabetes mellitus (DM)
Association of diabetes mellitus with coronary atherosclerotic plaque burden and morphology measured by multidetector computed coronary angiography / قياس مدى ارتباط داء السكرى بالعبء الناتج عن اللويحة المتصلبة بالشرايين التاجية و شكلها باستخدام الاشعة المقطعية متعددة المقاطع للشرايين التاجية Reem Mohamed Hamed Elshall ; Supervised Noha Hossam Eldein Ibrahim Behaire , Hazem Hamed A. Elhafiz Soliman - Cairo : Reem Mohamed Hamed Elshall , 2017 - 103 P. : facsimiles ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Radio-diagnosis
Background: Coronary artery disease (CAD) is a leading cause of morbidity and mortality in patients with diabetes mellitus (DM). Diabetics have more prevalent, extensive coronary atherosclerosis than non-diabetics, with an accelerated progression and higher prevalence of multi-vessel disease. Diabetics have also a higher prevalence of silent atherosclerotic lesions and asymptomatic ischemia, making the diagnosis of CAD easier to miss and allowing the disease to progress to an advanced stage before becoming clinically evident. Objectives: To identify the features of CAD in diabetic patients using coronary CT angiography (CCTA). Conclusion: Diabetes is an independent predictor of CAD and is also associated with more advanced CAD, evaluated by indexes of coronary atherosclerotic burden. The comprehensive information regarding the presence, severity and type of plaque noninvasively provided by CCTA, has made possible a detailed characterization of the coronary disease pattern of diabetic patients at an earlier stage of disease. Diabetics have a significantly higher prevalence of plaques in every anatomical subset (number of vessel and either proximal or distal localizations) and for the different plaque composition (higher prevalence of mixed plaque). Since mixed plaque is associated with worse long-term clinical outcomes, these findings support more aggressive preventive measures in this population
Atherosclerotic burden Coronary atherosclerotic plaque (CAP) Diabetes mellitus (DM)