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New approaches for the synthesis of heterocyclic compounds containing nitrogen and sulfur and assessment of their cytotoxicity /

Ahmed Mohamed Mahmoud Abdelkhalek Sarhan

New approaches for the synthesis of heterocyclic compounds containing nitrogen and sulfur and assessment of their cytotoxicity / إتجاهات جديدة لتحضير مركبات غير متجاَنسة الحلقة محتوية على عنصرى النيتروجين والكبريت و تقييم درجة سميتها Ahmed Mohamed Mahmoud Abdelkhalek Sarhan ; Supervised Rafat Milad Mohareb - Cairo : Ahmed Mohamed Mahmoud Abdelkhalek Sarhan , 2016 - 142 P. ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Organic Chemistry

The thesis contains one original work: New approaches for the synthesis of heterocyclic compounds containing nitrogen and sulfur and assessment of their cytotoxicity. In this work the ethyl 4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (1) reacted with phenylisothiocyanate (2) to give the N-phenylthiourea derivative 3.Specialized through the synthesis and cytotoxicity evaluation of new heterocyclic compounds containing nitrogen and/or sulfur with potential biological activities towards some cancer cell lines. Among the synthesized compounds, the thiophene, thiazole, pyrazole, pyridine and pyrimidine derivatives



Containing nitrogen and sulfur The synthesis of heterocyclic compounds Thiophene systems