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Comparative study between subfoveal choroidal thickness in glaucomatous eyes and in normal age matched population using spectral domain optical coherence tomography /

Safaa Galal Abdelkodous

Comparative study between subfoveal choroidal thickness in glaucomatous eyes and in normal age matched population using spectral domain optical coherence tomography / دراسة مقارنة بين سمك المشيمة تحت ماقولة العين فى العيون المريضة بالمياه الزرقاء و العيون الطبيعية لاشخاص مشابهين فى السن باستخدام الماسح الضوئى المقطعى التوافقى الطيفى Safaa Galal Abdelkodous ; Supervised Soheir Mohammed Esmat , Heba Magdy Ahmed , Mohammed Mahmoud Khafagy - Cairo : Safaa Galal Abdelkodous , 2017 - 124 P. : charts , facsimiles ; 25cm

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Ophthalmology

Aim of work: To compare subfoveal choroidal thickness measurements in primary angle closure glaucoma (PACG), primary open angle glaucoma (POAG) patients, and normal age matched population, and to correlate between the subfoveal choroidal thickness with each of the average peripapillary retinal nerve fiber layer (RNFL) thickness, the average ganglion cell complex (GCC) thickness, as well as Humphrey field analyzer parameters in these patients mainly the mean deviation (MD) and pattern standard deviation (PSD). Methods: Cross sectional observational case-control study. The study included 124 eyes; 40 eyes of PACG patients, 42 eyes of POAG patients and 42 eyes of normal controls. Measurement of the subfoveal choroidal thickness was done using SD-OCT in the cross line scan. Results: There was no significant difference in subfoveal choroidal thickness among normal eyes, eyes with POAG and eyes with PACG (All P values >0.05). There was also a significant weak positive correlation between choroidal thickness and average RNFL thickness (r=0.804, p value <0.001). In addition, thinner choroid was associated with older age (r= -0.264, P value = 0.003) and myopic refraction (r=0.243, P value = 0.007), while thicker choroid was related to a better visual acuity (r=0.199, P value =0.026). Also, there was no significant inter-observer variation for choroidal thickness measurements P value =0.161



Glaucoma Spectral domain optical coherence tomography Subfoveal choroidal thickness