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Potential therapeutic effect of amlodipine and thymoquinone alone or in combination on traumatic brain injury in mice /

Asmaa Ahmed Gomaa Mohamed

Potential therapeutic effect of amlodipine and thymoquinone alone or in combination on traumatic brain injury in mice / التأثير العلاجي المحتمل للأملودبين والثيموكينون منفردين أو مجتمعين في حالات أصابات الدماغ في الفئران Asmaa Ahmed Gomaa Mohamed ; Supervised Hanan Salah Eldin Elabhar , Azza Sayed Mohmed Awad - Cairo : Asmaa Ahmed Gomaa Mohamed , 2017 - 191 P. : charts , facsimiles ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology

Thaumatic Brain Injury (TBI) is one of the major medical and socioeconomic problems that can be fatal and disabling. TBI is a complex pathophysiological cascade including oxidative stress (OS), inflammatory process, abnormal accumulation of intracellular calcium, and cell death. Purpose: This study aimed to evaluate the potential therapeutic effect of thymoquinone, amlodipine, and their combination against TBI model. Study Design : Male albino mice were allocated into sham, TBI, and TBI treated with thymoquinone, amlodipine, their combination for one week



Amlodipine TBI Thymoquinone