Synthesis of Novel Heterocycle derivatives as potential phosphodiesterase inhibitors and anticancer /
Rowaida Adel Abdelhamid Hassan
Synthesis of Novel Heterocycle derivatives as potential phosphodiesterase inhibitors and anticancer / تشييد مشتقات جديدة من متعددة الحلقة وتقييمها كمثبطات لإنزيمات الفوسفودايستريزو كمضات للسرطان Rowaida Adel Abdelhamid Hassan ; Supervised Ashraf H. Abadi , Mohammed Abdelhalim - Cairo : Rowaida Adel Abdelhamid Hassan , 2017 - 102 Leaves : charts , facsimiles ; 30cm
Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry
Cyclicn nucleotide phosphodiesterase (PDEs) are promising targets for pharmacological ontervention. The presence of multiple PDE genes, diversity of the isoforms produced from each gene, selective tissue and cellular expression of the isoforms compartmentation within cells, and an array of conformations of PDE proteins are some of the properties that challenge the development of drugs that target these enzymes
Anticancer Cyclicn nucleotide phosphodiesterase (PDEs) Phosphodiesterase inhibitors
Synthesis of Novel Heterocycle derivatives as potential phosphodiesterase inhibitors and anticancer / تشييد مشتقات جديدة من متعددة الحلقة وتقييمها كمثبطات لإنزيمات الفوسفودايستريزو كمضات للسرطان Rowaida Adel Abdelhamid Hassan ; Supervised Ashraf H. Abadi , Mohammed Abdelhalim - Cairo : Rowaida Adel Abdelhamid Hassan , 2017 - 102 Leaves : charts , facsimiles ; 30cm
Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry
Cyclicn nucleotide phosphodiesterase (PDEs) are promising targets for pharmacological ontervention. The presence of multiple PDE genes, diversity of the isoforms produced from each gene, selective tissue and cellular expression of the isoforms compartmentation within cells, and an array of conformations of PDE proteins are some of the properties that challenge the development of drugs that target these enzymes
Anticancer Cyclicn nucleotide phosphodiesterase (PDEs) Phosphodiesterase inhibitors