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Impact of short non-coding RNAs on lipid droplet formation via targeting LDLR /

Merna Hatem Mohamed Abelhafeiz

Impact of short non-coding RNAs on lipid droplet formation via targeting LDLR / Merna Hatem Mohamed Abelhafeiz ; Supervised Ahmed Ihab Abdelaziz , Injie Omer Fawzy - Cairo : Merna Hatem Mohamed Abelhafeiz , 2017 - 76 Leaves : charts , facsimiles ; 30cm

Thesis (M.Sc.) - Garman University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmacology and Toxicology

Low-density lipoprotein receptor (LDLR), a member of LDLR family, has been identified as a cell surface receptor reponsible for lipid uptake and homeostasis. Abnormal hepatic lipid regulation can lead to excess accumulation of intracellular fats, thus contributing to one of the major health problems woirldwide, non-alconholic fatty liver disease (NAFLD)