Expression of Micro RNAs 206 and 133b and serum IL-17 levels in preeclamptic females /
Ayman Mohammed Hany
Expression of Micro RNAs 206 and 133b and serum IL-17 levels in preeclamptic females / فى النساء اللآى يعانين من تسمم الحملIL-17ومستوى مصل b133, 306التعبير الجين لميكرو ار ان ايه Ayman Mohammed Hany ; Supervised Yasser Hussein Nassar, Mostafa Mohammed Mostafa , Salah Aly Sanad - Cairo : Ayman Mohammed Hany , 2017 - 156 P. : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Medical Biochemistry
The human placenta is a rapidly evolving organ that harbors a rich and diverse transcriptome. It is estimated that 66% of all human proteins are expressed in the placenta (Uhlen et al., 2016). Not surprisingly, the human placenta also expresses numerous types of miRNA species, with a fraction of these species being specific to trophoblasts (Luo et al., 2009).MicroRNAs (miRNAs) are small noncoding RNAs that act at a posttranscriptional level to degrade target genes recognized by complementary base pairing in the 3untranslated region of the mRNA.Through inhibition of protein translation or promotion of mRNA degradation, miRNAs have roles in physiological and pathological processes such as cell differentiation, proliferation/growth, apoptosis, angiogenesis, inflammation, redox signaling and other endothelial cell functions (Zhang 2008). Since these processes are disrupted in preeclampsia,miRNAs can potentially play significant roles in preeclampsia pathogenesis. miRNAs may provide a novel strategy for better understanding of preeclampsia and its diagnosis
133b Micro RNAs 206 Serum IL-17
Expression of Micro RNAs 206 and 133b and serum IL-17 levels in preeclamptic females / فى النساء اللآى يعانين من تسمم الحملIL-17ومستوى مصل b133, 306التعبير الجين لميكرو ار ان ايه Ayman Mohammed Hany ; Supervised Yasser Hussein Nassar, Mostafa Mohammed Mostafa , Salah Aly Sanad - Cairo : Ayman Mohammed Hany , 2017 - 156 P. : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Medical Biochemistry
The human placenta is a rapidly evolving organ that harbors a rich and diverse transcriptome. It is estimated that 66% of all human proteins are expressed in the placenta (Uhlen et al., 2016). Not surprisingly, the human placenta also expresses numerous types of miRNA species, with a fraction of these species being specific to trophoblasts (Luo et al., 2009).MicroRNAs (miRNAs) are small noncoding RNAs that act at a posttranscriptional level to degrade target genes recognized by complementary base pairing in the 3untranslated region of the mRNA.Through inhibition of protein translation or promotion of mRNA degradation, miRNAs have roles in physiological and pathological processes such as cell differentiation, proliferation/growth, apoptosis, angiogenesis, inflammation, redox signaling and other endothelial cell functions (Zhang 2008). Since these processes are disrupted in preeclampsia,miRNAs can potentially play significant roles in preeclampsia pathogenesis. miRNAs may provide a novel strategy for better understanding of preeclampsia and its diagnosis
133b Micro RNAs 206 Serum IL-17