Effect of cyclin D1 on the prognosis of multiple myeloma in Egyptian patients /
Menna Alla Mohie Eldein Elsayed Sherif
Effect of cyclin D1 on the prognosis of multiple myeloma in Egyptian patients / على التطور الأكلينيكى فى المرضى المصريين المصابين بالورم النقوى المتعدد D1 تأثير السيكلين Menna Alla Mohie Eldein Elsayed Sherif ; Supervised Lalia Abdelrahman Hegazy , Osman Mohamed Mansour , Reham Ahmed Rashed - Cairo : Menna Alla Mohie Eldein Elsayed Sherif , 2018 - 129 P. : charts , facsimiles ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology
Background: Multiple myeloma is a disseminated malignancy of monoclonal plasma cells, diagnosed by 10% clonal bone marrow plasma cells or a biopsy infiltrated by plasma cells along with one or more of the multiple myeloma defining events (MDE): CRAB (hypercalcemia, renal failure, anemia, or lytic bone lesions). Aim of work: Correlating Cyclin D1 with the prognosis of the patients. Subjects, materials and methods: Bone marrow biopsy of 50 patients newly diagnosed as Multiple myeloma were examined by immunohistochemistry for Cyclin D1, then these patients were followed up for a year. Results: There was significant correlation between Cyclin D1 and response of the patients. Conclusion: Cyclin D1 positive patients were found more likely to have worse prognosis than the negative ones
Cyclin D1 Immunohistochemistry Multiple Myeloma
Effect of cyclin D1 on the prognosis of multiple myeloma in Egyptian patients / على التطور الأكلينيكى فى المرضى المصريين المصابين بالورم النقوى المتعدد D1 تأثير السيكلين Menna Alla Mohie Eldein Elsayed Sherif ; Supervised Lalia Abdelrahman Hegazy , Osman Mohamed Mansour , Reham Ahmed Rashed - Cairo : Menna Alla Mohie Eldein Elsayed Sherif , 2018 - 129 P. : charts , facsimiles ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology
Background: Multiple myeloma is a disseminated malignancy of monoclonal plasma cells, diagnosed by 10% clonal bone marrow plasma cells or a biopsy infiltrated by plasma cells along with one or more of the multiple myeloma defining events (MDE): CRAB (hypercalcemia, renal failure, anemia, or lytic bone lesions). Aim of work: Correlating Cyclin D1 with the prognosis of the patients. Subjects, materials and methods: Bone marrow biopsy of 50 patients newly diagnosed as Multiple myeloma were examined by immunohistochemistry for Cyclin D1, then these patients were followed up for a year. Results: There was significant correlation between Cyclin D1 and response of the patients. Conclusion: Cyclin D1 positive patients were found more likely to have worse prognosis than the negative ones
Cyclin D1 Immunohistochemistry Multiple Myeloma