Synthesis of novel heterocyclic compounds utilizing active methylene reagents and thiols as precursors /
Hadeer Mohamed Diab Elhosseny
Synthesis of novel heterocyclic compounds utilizing active methylene reagents and thiols as precursors / تشييد مركبات حلقية غير متجانسة جديدة باستخدام مواد محتوية على مجموعة الميثيلين النشطة و الثيولات كبادئات اولية Hadeer Mohamed Diab Elhosseny ; Supervised Ahmed Helmy Mahmoud Elwahy , Ismail Abdelshafy Abdelhamid - Cairo : Hadeer Mohamed Diab Elhosseny , 2018 - 154 P. ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Organic Chemistry
Part1:A new series of poly(tetrahydrobenzimidazo[2,1-b]quinazolin-1(2H)-ones) was synthesized using a multicomponent reaction of poly(aldehydes), dimedone and 2-aminobenzimidazole in DMF under conventional heating as well as under microwave irradiation.Part 2:The synthetic utility of 3-thioxo-1,2,4-triazin-5-ones 1 and4-amino-3-mercapto-1,2,4-triazin-5(4H)-ones 2 as building blocks for novel bis- and poly(1,2,4-triazines) via alkylation with the corresponding bis- and poly(halo)compounds was investigated. Prediction of the site of alkylationhas been confirmed using spectroscopic data.The reactivity of the novel bis-amines towards aromatic mono- and bis(aromatic aldehyde) has also been investigated.Keywords:Poly(aldehydes),dimedone, 2-aminobenzimidazole,cyclocondensation, Michael addition, poly(alkylation), poly(tetrahydrobenzimidazoquinazolinone), 3-thioxo-1,2,4-triazin-5-one, 4-amino-3-mercapto-1,2,4-triazin-5(4H)-one, alkylation, bis-triazine, poly-triazine, condensation
2-aminobenzimidazole Dimedone Poly(aldehydes)
Synthesis of novel heterocyclic compounds utilizing active methylene reagents and thiols as precursors / تشييد مركبات حلقية غير متجانسة جديدة باستخدام مواد محتوية على مجموعة الميثيلين النشطة و الثيولات كبادئات اولية Hadeer Mohamed Diab Elhosseny ; Supervised Ahmed Helmy Mahmoud Elwahy , Ismail Abdelshafy Abdelhamid - Cairo : Hadeer Mohamed Diab Elhosseny , 2018 - 154 P. ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Organic Chemistry
Part1:A new series of poly(tetrahydrobenzimidazo[2,1-b]quinazolin-1(2H)-ones) was synthesized using a multicomponent reaction of poly(aldehydes), dimedone and 2-aminobenzimidazole in DMF under conventional heating as well as under microwave irradiation.Part 2:The synthetic utility of 3-thioxo-1,2,4-triazin-5-ones 1 and4-amino-3-mercapto-1,2,4-triazin-5(4H)-ones 2 as building blocks for novel bis- and poly(1,2,4-triazines) via alkylation with the corresponding bis- and poly(halo)compounds was investigated. Prediction of the site of alkylationhas been confirmed using spectroscopic data.The reactivity of the novel bis-amines towards aromatic mono- and bis(aromatic aldehyde) has also been investigated.Keywords:Poly(aldehydes),dimedone, 2-aminobenzimidazole,cyclocondensation, Michael addition, poly(alkylation), poly(tetrahydrobenzimidazoquinazolinone), 3-thioxo-1,2,4-triazin-5-one, 4-amino-3-mercapto-1,2,4-triazin-5(4H)-one, alkylation, bis-triazine, poly-triazine, condensation
2-aminobenzimidazole Dimedone Poly(aldehydes)