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Hypertonic saline for goal-directed therapy guided by capstesia{u036D} {u036B} in gastrointestinal surgeries : A randomized controlled study /

Abdelrahman Mohamed Saad

Hypertonic saline for goal-directed therapy guided by capstesia in gastrointestinal surgeries : A randomized controlled study / المحلول الملحى مفرط التوتر للعلاج الموجه نحو الهدف نسترشد كبستيزيا فى عمليات الجهاز الهضمى : دراسه عشوائيه محكمه Abdelrahman Mohamed Saad ; Supervised Yasser Mohamed Hamed Elhalafaway , Essam Abdelhalem Mahran , Hany Mohammed Elhadi Shoukat - Cairo : Abdelrahman Mohamed Saad , 2018 - 111 P. : charts , facsimiles ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Anaesthesia

Hypertonic saline (HS) solutions restore the macro-and the micro-circulation by a combination of osmotic-induced plasma volume expansion, arteriolar vasodilation, and capillary endothelial shrinkage. Also, hypertonicity may ameliorate the detrimental consequences on the immune function of trauma, shock, reperfusion, and major surgery that may lead to organ dysfunction. The concept of intraoperative goal-directed fluid therapy (GDFT) has been studied aiming to increase stroke volume and cardiac output, improve gut perfusion, decrease gut mucosal acidosis and complications. Goal directed therapy (GDT) utilizes several types of invasive and non-invasive monitoring techniques that influence the decisions to give intravenous fluids, start vasopressors, or initiate inotropes on a patient



Gastrointestinal surgeries Goal-directed therapy Hypertonic saline