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Tamoxifen-melatonin hybrid ligands as novel potent agents against breast cancer /

Mohamed Akmal Mohamed Aly Marzouk

Tamoxifen-melatonin hybrid ligands as novel potent agents against breast cancer / الروابط الهجينية التاموكسيفين- الميلاتونين كمواد جديدة قوية ضد سرطان الثدي Mohamed Akmal Mohamed Aly Marzouk ; Supervised Darius P. Zlotos - Cairo : Mohamed Akmal Mohamed Aly Marzouk , 2018 - 185 Leaves : charts , facsimiles ; 30cm

Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry

Breast cancer is one of the most common type of cancer among woman worldwide.Tamoxifen is commonly used to prevent and treat estrogen receptor positive (ER+) breast cancer. However, its chronic use can increase the risk of uterine cancer and induce tamoxifen resistance