Study of PDA in preterm infants in tertiary neonatal intensive care unit : Prevalence, complications and management /
Elham Abdelmonsef Sultan
Study of PDA in preterm infants in tertiary neonatal intensive care unit : Prevalence, complications and management / دراسة عن الوصلة الشريانية المفتوحة بين الشريان الرئوى والشريان الأورطى فى الرعاية المركزة للأطفال حديثى الولادة : معدل الحدوث: المضاعفات و طرق العلاج Elham Abdelmonsef Sultan ; Supervised Fatma Alzahraa Mostafa Gomaa , Reem Mahmoud Badr Eldeen , Antoine Fakhry Abdelmassih - Cairo : Elham Abdelmonsef Sultan , 2019 - 136 P. : charts , facsimiles ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics
Background: Patent ductus arteriosus poses diagnostic and therapeutic dilemma for clinicans, diagnosis of persistent PDA and determination of its clinical and hemodynamic significance are challenging. Method: Prospective observational study of 152 neonates with gestational age 34 weeks in which clinical parameters (prenatal: maternal risk factor, use of corticosteroid, mode of delivery. perinatal: gestational age, birth weight, Apgar score, gender. postnatal: heart rate, wide pulse pressure, blood pressure, oxygen therapy, blood gases, lactate level. outcomes; sepsis, apnea, NEC,IVH,BPD, pulmonary haemorrhage and echocardiographic parameters(duct size, left atrium /aortic ratio).the clinical and echocardiographic parameters analyzed were considerd statistically significant when P<0.05. Result: In the 152 neonates, the incidence of PDA was 87 (57.2%): (54(62.1%) non HSPDA and 33(37.9%) HSPDA) that received medical treatment (paracetamol 15mg/kg/6hr IV for 3 days) follow up Echo done at day 7 of life showed 20(68,9%) cases after 1st course,4 died before the day of follow up, 9 cases received 2nd course paracetamol. follow up Echo showed 4(13.7%) cases closed, 5 cases failed closure assigned for surgical ligation. the group of non HSPDA show spontaneous closure after conservative treatment. no PDA group was 65 (42.8%) that showed 2 reopened PDA.co-morbidities such as sepsis, pulmonary hemorrhage significantly associated to PDA and HSPDA groups. mortality was higher in HSPDA group than non HSPDA group
Echocardiograph Patent Ductus Arteriosus Preterm
Study of PDA in preterm infants in tertiary neonatal intensive care unit : Prevalence, complications and management / دراسة عن الوصلة الشريانية المفتوحة بين الشريان الرئوى والشريان الأورطى فى الرعاية المركزة للأطفال حديثى الولادة : معدل الحدوث: المضاعفات و طرق العلاج Elham Abdelmonsef Sultan ; Supervised Fatma Alzahraa Mostafa Gomaa , Reem Mahmoud Badr Eldeen , Antoine Fakhry Abdelmassih - Cairo : Elham Abdelmonsef Sultan , 2019 - 136 P. : charts , facsimiles ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics
Background: Patent ductus arteriosus poses diagnostic and therapeutic dilemma for clinicans, diagnosis of persistent PDA and determination of its clinical and hemodynamic significance are challenging. Method: Prospective observational study of 152 neonates with gestational age 34 weeks in which clinical parameters (prenatal: maternal risk factor, use of corticosteroid, mode of delivery. perinatal: gestational age, birth weight, Apgar score, gender. postnatal: heart rate, wide pulse pressure, blood pressure, oxygen therapy, blood gases, lactate level. outcomes; sepsis, apnea, NEC,IVH,BPD, pulmonary haemorrhage and echocardiographic parameters(duct size, left atrium /aortic ratio).the clinical and echocardiographic parameters analyzed were considerd statistically significant when P<0.05. Result: In the 152 neonates, the incidence of PDA was 87 (57.2%): (54(62.1%) non HSPDA and 33(37.9%) HSPDA) that received medical treatment (paracetamol 15mg/kg/6hr IV for 3 days) follow up Echo done at day 7 of life showed 20(68,9%) cases after 1st course,4 died before the day of follow up, 9 cases received 2nd course paracetamol. follow up Echo showed 4(13.7%) cases closed, 5 cases failed closure assigned for surgical ligation. the group of non HSPDA show spontaneous closure after conservative treatment. no PDA group was 65 (42.8%) that showed 2 reopened PDA.co-morbidities such as sepsis, pulmonary hemorrhage significantly associated to PDA and HSPDA groups. mortality was higher in HSPDA group than non HSPDA group
Echocardiograph Patent Ductus Arteriosus Preterm