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Acute kidney injury in Preterm newborns : Incidence, Risk factors & outcome /

Michael Sabri Atia Shenoda Ibrahem

Acute kidney injury in Preterm newborns : Incidence, Risk factors & outcome / نسبة الحدوث عوامل الخطر والنتائج : إصابات الكلى الحادة لحديثى الولادة ناقصى النمو Michael Sabri Atia Shenoda Ibrahem ; Supervised Heba Hany Abuhussein , Doaa Mohamed Salah , Rasha Elkaffas - Cairo : Michael Sabri Atia Shenoda Ibrahem , 2020 - 102 p . : charts , facsmilies ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics

Background: Acute kidney injury (AKI) is a serious common morbidity in premature neonates. Predicting AKI on the basis of risk factors may help in early intervention and improved outcome. The aim of this study is to identify the incidence, predisposing factors, and outcome of AKI in neonates admitted in NICU, Cairo University Children Hospital during the study period. Methods: One hundred and twenty premature neonates were observed for occurrence of AKI, associated morbidity, potential risk factors and their clinical outcomes during their NICU admission. Results: AKI was reported in 42.5% of included premature neonates with 80% of AKI group were stage 1 AKI. low birth weight, mechanical ventilation support, PDA, intra-ventricular hemorrhage, perinatal asphyxia, low diastolic blood pressure, parenteral feeding and nephrotoxic agents could be potential risk factors for development of AKI in preterm neonates (p<0.05). AKI group had significantly longeduration of hospital stay (p= 0.001) but insignificantly increased mortality (p=0.114) than those without AKI. Conclusion: AKI is common in preterm neonates. Many potentially modifiable risk factors are incriminated in development of AKI in this vulnerable group. AKI is associated with less favorable patient outcome than if preliminary prevented



Common Morbidity Modifiable Risk Mortality