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The effect of platlet-rich plasma on pain score and frequency of luxation in temporomandibular joint subluxation : A prospective randomized placepo controlled trail /

Abdelrahman Soliman Alatyeh

The effect of platlet-rich plasma on pain score and frequency of luxation in temporomandibular joint subluxation : A prospective randomized placepo controlled trail / تقييم تأثير البلازما الغنية بالصفحيات المستخدمة للمعالجة بالحقن على تواتر خلع المفصل الفكى الصدغى : مقارنة مع مادة غير فعالة Abdelrahman Soliman Alatyeh ; Supervised Hamida Refai Hassanien , Osama Taema - Cairo : Abdelrahman Soliman Alatyeh , 2020 - 101 P. : charts , facsimiles , photoghraphs ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Oral and Maxillofacial Surgery

Aim: The aim of this study is to clinically assess the efficacy of PRP prolotherapy for treatment of TMJ subluxation.Methodology: A prospective, randomized placebo controlled clinical trial including patients with temporomandibular joint subluxation.The study comprised 34 patients. Patients were randomly divided into 2 groups: control group (Saline) , active group (PRP) Each patient in both groups received 2 treatment sessions of intra-articular and pericapsular injections 2 weeks apart. Visual analog scale of TMJ pain intensity, maximum mouth opening (MMO), joint sounds, and frequency of luxations were clinically assessed and documented preoperatively and postoperatively at 6, 12 and 30 weeks after treatment. Results: Both groups showed statistically significant improvement in TMJ pain, frequency of luxations and clicking after 6, 12 and 30 weeks Comparison between the two groups showed insignificant differences in all the assessed parameters at any time point. Conclusions The results of this study highlight the beneficial effects of both saline and PRP injections in patients with TMJ subluxation and demonstrate that PRP prolotherapy is not more effective than placebo in treatment of TMJ subluxation



Frequency of luxation in temporomandibular Pain score Platlet-rich plasma