Pharmaceutical study on a model drug in certain ocular drug delivery systems / (Record no. 162337)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03838namaa22004211i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20240211192337.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 231021s2023 ua a|||frm 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GICUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GICUC |
| Modifying agency | EG-GICUC |
| Description conventions | rda |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| Language code of summary or abstract | eng |
| -- | ara |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposit |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 615.704 |
| Edition number | 21 |
| 092 ## - LOCALLY ASSIGNED DEWEY CALL NUMBER (OCLC) | |
| Classification number | 615.704 |
| Edition number | 21 |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.10.M.Sc.2023.Mi.P |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Mina Josef Azmy, |
| Relator term | preparation. |
| 245 10 - TITLE STATEMENT | |
| Title | Pharmaceutical study on a model drug in certain ocular drug delivery systems / |
| Statement of responsibility, etc. | by Mina Josef Azmy ; under the supervision of Prof. Dr. Mohamed Ahmed El-Nabarawi, Assoc. Prof. Dr. Mahmoud Hassan Teaima, Assoc. Prof. Dr. Mennatallah Mohamed Abdellatif. |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسة صيدلية على نموذج عقار في بعض أنظمة الدواء المستخدمة للعين |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 2023. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 83 pages : |
| Other physical details | illusturations ; |
| Dimensions | 25 cm. + |
| Accompanying material | CD. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | Unmediated |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | volume |
| Source | rdacarrier |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.)-Cairo University, 2023. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Bibliography: pages 67-83. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Keratomycosis, or fungal keratitis, is a potentially serious consequence that can result in visual abnormalities or even blindness if treatment is delayed. STZN isan imidazole antifungal drug that effectively treats Candida albicans infections and some species ofFusarium and Aspergillus. LP was chosen as a potential nanocarrier for enhancing the corneal penetration and deposition of STZN, as the presence of a positive charge facilitates vesicle adhesion onto the negatively charged sialic acid moieties found in the mucus membrane on the corneal surface, resulting in higher corneal retention, minimizing drug elimination by lachrymal flow and improves the transcorneal flux. Also, the apparent advantage of small PS is that it creates a large contact surface with the ocular surface, allowing enhanced corneal absorption. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | يعتبر الاصابة بفطريات قرنية العين، أو التهاب القرنية الفطري ، نتيجة خطيرة محتملة يمكن أن تؤدي إلى تشوهات بصرية أو حتى العمى إذا تأخر العلاج. نترات سيرتاكونازول (STZN) هو دواء مضاد للفطريات فعال للغاية في علاج عدوى Fusarium sppو Candida spp و Aspergillus spp. تم اختيار LP كحامل نانوي محتمل لتعزيز اختراق القرنية لSTZN حيث أن وجود شحنة موجبة يسهل التصاق الحويصلة على شقوق حمض السياليك سالبة الشحنة الموجودة في الغشاء المخاطي على سطح القرنية ، مما يؤدي إلى ارتفاع احتباس القرنية ، وتقليل ازالة الادوية عن طريق التدفق الدمعي ويحسن التدفق عبر القرنية. أيضًا ، تتمثل الميزة الواضحة لحجم الجسيمات الصغير في أنها تخلق سطح تلامس كبير مع سطح العين ، مما يسمح بامتصاص القرنية المعزز. |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issues also as CD. |
| 546 ## - LANGUAGE NOTE | |
| Language note | Text in English and abstract in Arabic & English. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Ophthalmic drugs. |
| 653 #0 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | STZN |
| -- | scanning calorimetry (DSC) |
| -- | Serum Inflammatory Biomarkers and BDG |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Ahmed El-Nabarawi, |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mahmoud Hassan Teaima, |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mennatallah Mohamed Abdellatif, |
| Relator term | thesis advisor. |
| 900 ## - EQUIVALENCE OR CROSS-REFERENCE-PERSONAL NAME [LOCAL, CANADA] | |
| Numeration | 01-01-2023 |
| Titles and other words associated with a name | Mohamed Ahmed El-Nabarawi. |
| -- | Mahmoud Hassan Teaima. |
| -- | Mennatallah Mohamed Abdellatif. |
| Universities | Cairo University |
| Faculties | Faculty of Pharmacy |
| Divisons | Department of Pharmaceutics and Industrial Pharmacy |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Asmaa |
| Reviser | Essam |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | |
| Edition | 21 |
| Suppress in OPAC | No |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type |
|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | Not for loan | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.10.M.Sc.2023.Mi.P | 01010110087672000 | 21.10.2023 | Thesis |