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Control of multi-drug resistant escherichia coli infecting the urinary tract in children / (Record no. 165685)

MARC details
000 -LEADER
fixed length control field 05264namaa22004211i 4500
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240211192450.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 231113s2022 ua a|||frm||| 000 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency EG-GICUC
Language of cataloging eng
Transcribing agency EG-GICUC
Modifying agency EG-GICUC
Description conventions rda
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title eng
Language code of summary or abstract eng
-- ara
049 ## - LOCAL HOLDINGS (OCLC)
Holding library Deposit
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 616.01442
Edition number 21
092 ## - LOCALLY ASSIGNED DEWEY CALL NUMBER (OCLC)
Classification number 616.01442
Edition number 21
097 ## - Thesis Degree
Thesis Level M.Sc
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
Classification number Cai01.12.05.M.Sc.2022.Ba.C
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Bassant Alaa Eldin Gomaa,
Relator term preparation.
245 10 - TITLE STATEMENT
Title Control of multi-drug resistant escherichia coli infecting the urinary tract in children /
Statement of responsibility, etc. Presented by Bassant Alaa Eldin Gomaa ; supervisors Prof. Amira Mohamed AbuTaleb, Dr. Sherif Mohamed Elnagdy.
246 15 - VARYING FORM OF TITLE
Title proper/short title مقاومه بكتريا الاشرشيا القولونية المقاومة للدواء والتي تصيب المجرى البولي للألطفال
264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Date of production, publication, distribution, manufacture, or copyright notice 2022.
300 ## - PHYSICAL DESCRIPTION
Extent 116 pages :
Other physical details illustrations ;
Dimensions 25 cm. +
Accompanying material CD.
336 ## - CONTENT TYPE
Content type term text
Source rdacontent
337 ## - MEDIA TYPE
Media type term Unmediated
Source rdamedia
338 ## - CARRIER TYPE
Carrier type term volume
Source rdacarrier
502 ## - DISSERTATION NOTE
Dissertation note Thesis (M.Sc.)-Cairo University, 2022.
504 ## - BIBLIOGRAPHY, ETC. NOTE
Bibliography, etc. note Bibliography: pages 90-115.
520 ## - SUMMARY, ETC.
Summary, etc. The UTI is one of the most common infections in<br/>children. Out of 850 urine samples, were collected from children suspected to have<br/>urinary tract infection (UTI), 400 samples showed positive cultures. Only 287 (71.75<br/>%) cases out of 400 were diagnosed as the UTI. The UTI was more common among<br/>females 173/287 (60.3 %) than males 114/287 (39.7 %). Children at the age between<br/>3–6 years old were the most susceptible to infection compared to other ages.<br/>Escherichia coli was the main causative pathogen 115/287 (40.06 %) followed by<br/>Klebsiella 50/287 (17.4 %). All isolates of E. coli were resistant to amoxicillin and<br/>ticarcillin. On the other hand, amikacin, meropenem, nitrofurantoin and imipenem<br/>were the most efficient antibiotics and succeeded in controlling high number of E. coli<br/>isolates (88.69 % - 96.52 %). Non ESBL non AmpC producing E. coli isolates were<br/>more susceptible to antibiotics and essential oils than ESBL and AmpC producing E.<br/>coli isolates. Cinnamon oil was the most effective oil against the different strains of E.<br/>coli (ESBL, AmpC and non ESBL non AmpC), followed by thyme, clove, rosemary,<br/>lemon grasses and peppermint. On the other hand, oils of castor, lavender, anise, and<br/>cumin were ineffective against the three strains of E. coli. It was found that MICs<br/>were decreased in cinnamon oil/antibiotic combinations compared to the oil or<br/>antibiotic separately. Fractional inhibitory concentrations indices (FICIs) were<br/>calculated to determine the interaction between cinnamon oil and the selected<br/>antibiotics against the multidrug resistant isolates of E. coli. The synergistic effect<br/>was observed only in cinnamon oil/gentamycin combination in all strains of E. coli<br/>(P-value <0.001). The cnf1 virulence gene was detected by PCR technique. However,<br/>the resistance of the ESBL and AmpC β-lactamase producing E. coli to antibiotics<br/>was statically non-significant in relation to the presence of the cnf1 gene. The lowest<br/>distribution of cnf1 gene was found among non-ESBL non-AmpC producing E. coli<br/>to the antibiotics was significantly related to the presence of the cnf1 gene.
520 ## - SUMMARY, ETC.
Summary, etc. يعد التهاب المسالك البولية أحد أكثر أنواع العدوى شيوعًا في<br/>أطفال. تم جمع 850 عينة بول من أطفال يشتبه في إصابتهم بالمرض<br/>التهاب المسالك البولية (UTI)، أظهرت 400 عينة إيجابية الزرع. فقط 287 (71.75<br/>%) من أصل 400 حالة تم تشخيصها على أنها التهاب المسالك البولية. وكان التهاب المسالك البولية أكثر شيوعا بين<br/>الإناث 173/287 (60.3%) مقابل الذكور 114/287 (39.7%). الأطفال في سن ما بين<br/>وكان الأطفال من 3 إلى 6 سنوات هم الأكثر عرضة للإصابة مقارنة بالأعمار الأخرى.<br/>كانت الإشريكية القولونية هي المسبب الرئيسي للمرض 115/287 (40.06%) يليها<br/>كليبسيلا 50/287 (17.4%). كانت جميع عزلات بكتريا E. coli مقاومة للأموكسيسيلين و<br/>تيكارسيلين. ومن ناحية أخرى، أميكاسين، ميروبينيم، نيتروفورانتوين وإيميبينيم<br/>كانت المضادات الحيوية الأكثر فعالية ونجحت في السيطرة على عدد كبير من بكتيريا الإشريكية القولونية
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE
Additional physical form available note Issues also as CD.
546 ## - LANGUAGE NOTE
Language note Text in English and abstract in Arabic & English.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Escherichia coli infections.
653 #0 - INDEX TERM--UNCONTROLLED
Uncontrolled term cinnamon oil
-- non ESBL non AmpC producing E. coli
-- synergistic effect
-- necrotoxin gene
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Amira Mohamed AbuTaleb,
Relator term thesis advisor.
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Sherif Mohamed Elnagdy,
Relator term thesis advisor.
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Dina Mohammed Ahmed Hassan,
Relator term thesis advisor.
900 ## - EQUIVALENCE OR CROSS-REFERENCE-PERSONAL NAME [LOCAL, CANADA]
Numeration 01-01-2022
Titles and other words associated with a name Amira Mohamed AbuTaleb
-- Sherif Mohamed Elnagdy
-- Dina Mohammed Ahmed Hassan
Dates associated with a name Mohamed Eweis
Universities Cairo University
Faculties Faculty of Science
Divisons Department of Botany and Microbiology
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Hanan
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Koha item type Thesis
Edition 21
Suppress in OPAC No
Holdings
Source of classification or shelving scheme Not for loan Home library Current library Date acquired Full call number Barcode Date last seen Koha item type
Dewey Decimal Classification Not for loan المكتبة المركزبة الجديدة - جامعة القاهرة قاعة الرسائل الجامعية - الدور الاول 11.02.2024 Cai01.12.05.M.Sc.2022.Ba.C 01010110087713000 13.11.2023 Thesis