MARC details
| 000 -LEADER |
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| fixed length control field |
05692namaa22004211i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
OSt |
| 005 - أخر تعامل مع التسجيلة |
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| control field |
20240525091655.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
240522s2023 |||a|||fr|m|| 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
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| Original cataloguing agency |
EG-GICUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GICUC |
| Modifying agency |
EG-GICUC |
| Description conventions |
rda |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| Language code of summary or abstract |
eng |
| Language code of sung or spoken text |
ara |
| 049 ## - Acquisition Source |
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| Acquisition Source |
Deposit |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
616.99449 |
| 092 ## - LOCALLY ASSIGNED DEWEY CALL NUMBER (OCLC) |
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| Classification number |
616.99449 |
| Edition number |
21 |
| 097 ## - Degree |
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| Degree |
M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| Local Call Number |
Cai01 19 04 M.Sc 2023 Ma.C |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
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| Authority record control number or standard number |
Majed Ahmed El-sayed Hussien, |
| Preparation |
preparation. |
| 245 10 - TITLE STATEMENT |
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| Title |
Clinico-Pathological Features of Breast Cancer and Impact on Survival in Elderly Patients / |
| Statement of responsibility, etc. |
By Majed Ahmed El-sayed Hussien ; Supervised by Prof. Dr. Hanan Ramadan Nassar Mohame, Prof. Dr. Amany Mohamed Helal, Prof. Dr. Amrallah Abd El-Moneem Mohamed Sayed |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
السمات السريريه لسرطان الثدي في المرضى كبار السن واثرها على معدل النجاه / |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
|---|
| Date of production, publication, distribution, manufacture, or copyright notice |
2023. |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
109 pages : |
| Other physical details |
illustrations ; |
| Dimensions |
25 cm. + |
| Accompanying material |
CD. |
| 336 ## - CONTENT TYPE |
|---|
| Content type term |
text |
| Source |
rda content |
| 337 ## - MEDIA TYPE |
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| Media type term |
Unmediated |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
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| Carrier type term |
volume |
| Source |
rdacarrier |
| 502 ## - DISSERTATION NOTE |
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| Dissertation note |
Thesis (M.Sc.)-Cairo University, 2023. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
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| Bibliography, etc. note |
Bibliography: pages 91-108. |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc. |
the objective of this study is to analyze clinic pathological features<br/>of breast cancer in elderly women and impact on survival.<br/>Patients and methods: retrospective analysis (SPSS) was conducted based on<br/>medical records of patients who were treated in National Cancer Institute, Cairo<br/>University and Meet-Ghamr Oncology Center in the period between January 2012<br/>and December 2016.<br/>Results: The study included 343 breast cancer patients with mean age 68.8±4.3<br/>years. About 82.8% of the included patients had negative history of taking OCPs.<br/>About 57.4% had other medical conditions than breast cancer. Hypertension<br/>(46.4%) and diabetes (30%) had the highest prevalence followed by cardiac<br/>diseases (11.4%). Other medical disorders as renal (0.9%), hepatic (2.9%) and<br/>respiratory diseases (2.0%) were reported with lower frequencies. Associated<br/>medical disorders did not affect the overall 3 and 5 years survival rate. The<br/>pathological type of 258 out of 343 breast cancers was invasive duct carcinoma.<br/>Invasive lobular carcinoma type had the 2nd common pathological types (7.9%).<br/>Other breast cancer pathological types had variable lesser frequencies. Regarding<br/>pathological grading, grade II had the highest frequency among all lesions (77%).<br/>About 61.8% of patients were T2 and 14.9% were T1 or T3. A percent of 41.1%<br/>were N0 while 24.5% were N1. Most of patients were M0 (94.2%). Estrogen<br/>receptors and Progesterone receptors positive lesion had the highest frequency<br/>(79.6%; 74.9% respectively). While, Herceptin receptors positive lesions<br/>frequency was low ( 1 5 . 5 % ) . A number of 339 patients (98.8%) underwent<br/>surgical removal of breast mass while 4 patients only did not undergo surgeries.<br/>Modified radical mastectomy (MRM) was the main surgery followed by BCS.<br/>Simple mastectomy was performed in 13 patients and toilet mastectomy was<br/>performed in 2 patients. Pathological type and grade did not affect the 3 and 5<br/>years patient survival. Expression of ER and PR was associated significantly with<br/>better survival. The 3 years disease free survival rate was 85.9% and 5 years<br/>disease free survival rate was 81.6% after exclusion of the 20 patients that had<br/>Mets at diagnosis for more accurate results as they were not supposed to become<br/>disease free at any time point during the study.<br/>Conclusion: breast cancer in elderly patients is aggressive from the time of<br/>diagnosis and so further studies are needed to evaluate better managemen |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
لقد تزايد معدل الاصابه بسرطان الثدى في كبار السن مع ارتفاع وسائل التشخيص والمسح، حيث يمثل التقدم في السن عامل خطوره على معدل النجاه ما لم يكن عائقا في تلقي العلاج كما هو الحال مع المرضى الاقل عمرا مع الاخذ بالاعتبار الحاله العامه والامراض المصاحبه لدى المرضى. ومن نتائج الرساله تبين ارتفاع نسبة تعافي المرضى بعد خضوعهم لعملية الاستئصال الجذري اكثر من التحفظي لاورام الثدي حيث تمثلت النسبه الاكبر لدى المرضى ذوي المراحل الاولى من الورم. <br/>يعد اختيار العلاج المناسب للمرضى كبار السن المصابين بسرطان الثدي تحديا فيما يتعلق بالحاله العامه للمرضى, الامراض المصاحبه والحاله النفسيه وتقبلهم للعلاج خاصة لمرضى القلب والكلى. كما يختلف قرار العلاج بناءا على مرحلة الورم ما بين علاج جراحي, كيماوي, اشعاعي, هرموني وعلاج موجه بعد دراسة بيولوجيا الورم. <br/> |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
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| Issues CD |
Issued also as CD |
| 546 ## - LANGUAGE NOTE |
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| Text Language |
Text in English and abstract in Arabic & English. |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Breast Cancer |
| Source of heading or term |
qrmak |
| 653 #0 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Breast Cancer |
| -- |
elderly patients |
| -- |
survival |
| -- |
adjuvant |
| -- |
palliative. |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Hanan Ramadan Nassar Mohamed |
| Relator term |
thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Amany Mohamed Helal |
| Relator term |
thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Amrallah Abd El-Moneem Mohamed Sayed |
| Relator term |
thesis advisor. |
| 900 ## - Thesis Information |
|---|
| Grant date |
01-01-2023 |
| Supervisory body |
Hanan Ramadan Nassar Mohamed |
| -- |
Amany Mohamed Helal |
| -- |
Amrallah Abd El-Moneem Mohamed Sayed |
| Universities |
Cairo University |
| Faculties |
Faculty of National Cancer Institute |
| Department |
Department of Medical Oncology |
| 905 ## - Cataloger and Reviser Names |
|---|
| Cataloger Name |
Eman Ghareeb |
| Reviser Names |
Huda |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |
| Edition |
21 |
| Suppress in OPAC |
No |
