Bone marrow aspirate concentrate (BMAC) on 3D printed Polycaprolactone (PCL) scaffold for ridge augmentation of horizontal alveolar defects in aesthetic zone : (Record no. 170070)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 06469namaa22004211i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - أخر تعامل مع التسجيلة | |
| control field | 20250223033406.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250108s2023 |||a|||f m||| 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloguing agency | EG-GICUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GICUC |
| Modifying agency | EG-GICUC |
| Description conventions | rda |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| Language code of summary or abstract | eng |
| -- | ara |
| 049 ## - Acquisition Source | |
| Acquisition Source | Deposit |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 617.605 |
| 092 ## - LOCALLY ASSIGNED DEWEY CALL NUMBER (OCLC) | |
| Classification number | 617.605 |
| Edition number | 21 |
| 097 ## - Degree | |
| Degree | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Local Call Number | Cai01.09.13.M.Sc.2023.Al.B |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Authority record control number or standard number | Alaa Aly Hassan Fouad Mohamed, |
| Preparation | preparation. |
| 245 10 - TITLE STATEMENT | |
| Title | Bone marrow aspirate concentrate (BMAC) on 3D printed Polycaprolactone (PCL) scaffold for ridge augmentation of horizontal alveolar defects in aesthetic zone : |
| Remainder of title | Clinical case series study / |
| Statement of responsibility, etc. | by Alaa Aly Hassan Fouad Mohamed ; Supervision of Prof. Dr. Yasmin Ahmed ِAbdullah Nassar, Dr. Mahmoud Hanafy Mahmoud. |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | : استخدام مُركَّز النخاع العظمي علي حامل ثلاثى الابعاد مطبوع من مادة البولي كابرو لاكتون لتدعيم العظام افقيا بالمنطقة الجمالية بالفم |
| Remainder of title | / دراسه سريريه تسلسليه |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 2023. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 164 pages : |
| Other physical details | illustrations ; |
| Dimensions | 25 cm. + |
| Accompanying material | CD. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Source | rda content |
| 337 ## - MEDIA TYPE | |
| Media type term | Unmediated |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | volume |
| Source | rdacarrier |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.)-Cairo University, 2023. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Bibliography: pages 120-160. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Purpose: The purpose of this study was to introduce a novel technique in horizontal alveolar ridge augmentation in aesthetic zone using BMAC loaded in 3D printed PCL scaffolds.<br/>Methodology: 7 patients were included in the study where customized 3D printed scaffolds made of Polycaprolactone were fabricated to augment the horizontal alveolar defects then bone marrow aspiration procedure was performed followed by concentration of the bone marrow aspirate using density gradient centrifugation to obtain bone marrow aspirate concentrate (BMAC) which was loaded on the scaffolds and fixed in the deficient ridges using micro-screws. After 6 months, Second stage surgery was performed that involved bone biopsy from the augmented ridge followed by dental implant placement .<br/>Results: No radiographic evidence of bone formation when the 6-month postoperative CBCT was imposed over the immediate postoperative CBCT. In addition, the histological analysis of the bone biopsy obtained showed well organized collagen fibers with no evidence of bone formation.<br/>Nevertheless, the soft tissue response to the introduced material was excellent which was manifested by absence of any signs of inflammation or wound dehiscence in the recipient site for 6 month follow up period.<br/>Conclusion: Polycaprolactone is a biocompatible material which is a good candidate for bone tissue engineering procedures. However, it possesses slow biodegradation rate which would adversely affect new bone formation. Therefore, it is recommended to introduce more hydrophilic materials to the PCL during scaffold fabrication to produce composite scaffolds with higher rate of biodegradation. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | أ. الهدف: الهدف من اجراء البحث هو اجراء تدعيم للعظم المتآكل افقيا بالمنطقة الجمالية بالفم باستخدام مركز النخاع العظمي علي حامل ثلاثي الابعاد مطبوع من مادة البولي كابرولاكتون <br/>ب. المنهجية: سبعا من المرضي يعانون من التآكل الافقي لعظم الفك العلوي المنطقة الجمالية بالفم تمت معالجتهم بطباعة الحامل ثلاثي الابعاد من مادة البولي كابرولاكتون مصمم خصيصا لكل مريض وسحب النخاع <br/>العظمي من العظام الحرقفية الأمامية للمرضي وتركيزه باستخدام جهاز الطرد المركزي و تحميل مركز النخاع <br/>العظمي علي الحامل ثلاثي الابعاد و وضع غرسات اسنان بعد 6 شهور من العملية الاولي لخمس من المرضي بسبب انسحاب اثنين من المرضي من البحث<br/>جـ. النتائج : التئام الجروح كان طبيعيا للغاية بدون اي التهاب بأماكن الجروح و عدم حدوث اي عدوي مما يؤكد علي سلامة و امان مادة البولي كابرولاكتون علي الانسجة الحية<br/>لا يوجد فارق بكمية العظام بالأشعة ثلاثية الابعاد بين الاشعة اتي تم عملها فورا بعد عملية التدعيم العظمي و الاشعة التي تم عملها بعد 6 اشهر من العملية , ايضا عند فحص العينة العظمية المأخوذة من المنطقة التي تم تدعيمها تحت الميكروسكوب,<br/> اثبتت وجود الياف الكولاجين دون دلالة واضحة علي تكوّن عظام بالمنطقة المدعومة بالبولي كابرولاكتون.<br/>د. الاستنتاجات : مادة البولي كابرولاكتون مادة امنة علي الانسجة الحية و لكنها تعاني من بطء في معدل ذوبانها في جسم الانسان مما يؤدي الي بطء تكون العظام الجديدة في المكان الذي يشغله الحامل ثلاثي الابعاد.<br/>لذلك فانه يجب في المستقبل اضافة مواد اخري تزيد من سرعة ذوبان الحامل البولي كابرولاكتوني بالإضافة الي الانتظار لمدة اطول قبل وضع غرسات الاسنان للتأكد من ذوبان الحامل نهائيا . |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Issues CD | Issues also as CD. |
| 546 ## - LANGUAGE NOTE | |
| Text Language | Text in English and abstract in Arabic & English. |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Oral Surgery |
| Source of heading or term | qrmak |
| 653 #0 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Ridge augmentation |
| -- | Bone tissue engineering (BTE) |
| -- | 3D printing |
| -- | Scaffolds |
| -- | Bone marrow aspirate concentrate (BMAC) |
| -- | polycaprolactone (PCL) |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yasmin Ahmed Abdullah Nassar |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mahmoud Hanafy Mahmoud El Sayed |
| Relator term | thesis advisor. |
| 900 ## - Thesis Information | |
| Grant date | 01-01-2023 |
| Supervisory body | Yasmin Ahmed Abdullah Nassar |
| -- | Mahmoud Hanafy Mahmoud El Sayed |
| Discussion body | Hussein Hatem Abdel Rahman |
| -- | Amr Amin Ghanem |
| Universities | Cairo University |
| Faculties | Faculty of Dentistry |
| Department | Department of Oral and Maxillofacial Surgery |
| 905 ## - Cataloger and Reviser Names | |
| Cataloger Name | Shimaa |
| Reviser Names | Huda |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Edition | 21 |
| Suppress in OPAC | No |
| Source of classification or shelving scheme | Home library | Current library | Date acquired | Inventory number | Full call number | Barcode | Date last seen | Effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 08.01.2025 | 90186 | Cai01.09.13.M.Sc.2023.Al.B | 01010110090186000 | 08.01.2025 | 08.01.2025 | Thesis |