Functional and Oncological Outcome of Parosteal Osteosarcoma Treated by Limb-Salvage Procedure/ (Record no. 170457)
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|---|---|
| fixed length control field | 07129namaa22004331i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - أخر تعامل مع التسجيلة | |
| control field | 20250223033419.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250127s2023 |||a|||f m||| 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloguing agency | EG-GICUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GICUC |
| Modifying agency | EG-GICUC |
| Description conventions | rda |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| Language code of summary or abstract | eng |
| -- | ara |
| 049 ## - Acquisition Source | |
| Acquisition Source | Deposit |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 617.471 |
| 092 ## - LOCALLY ASSIGNED DEWEY CALL NUMBER (OCLC) | |
| Classification number | 617.471 |
| Edition number | 21 |
| 097 ## - Degree | |
| Degree | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Local Call Number | Cai01.11.25.Ph.D.2023.Ho.F |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Authority record control number or standard number | Hosam Mohamed Elsayed Foda, |
| Preparation | preparation. |
| 245 10 - TITLE STATEMENT | |
| Title | Functional and Oncological Outcome of Parosteal Osteosarcoma Treated by Limb-Salvage Procedure/ |
| Statement of responsibility, etc. | Hosam Mohamed Elsayed Foda ; Supervisors : Prof. Dr. Ashraf Elnahal, Prof. Dr. Walid Atef Ebeid, Dr. Wesam Abousenna. |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | /النتائج الوظيفية والورميه لمرض سرطان العظم الجارسمحاقي المعالج بطريقة انقاذ الطرف |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 2023. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 135 pages : |
| Other physical details | illustrations ; |
| Dimensions | 25 cm. + |
| Accompanying material | CD. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Source | rda content |
| 337 ## - MEDIA TYPE | |
| Media type term | Unmediated |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | volume |
| Source | rdacarrier |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D)-Cairo University, 2023. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Bibliography: pages 130-135. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Parosteal osteosarcoma (PO) is a typically well-differentiated subtype of osteosarcoma, with slow growth and low-grade malignancy that do not tend to metastasize.<br/>Parosteal osteosarcoma (PO) is the most common type of osteosarcoma arising on the bone periosteum and accounts for 2%-4% of all primary malignant bone tumors, approximately 4%-6% of all osteosarcomas, and 70% of surface osteosarcomas.[3]<br/>Parosteal osteosarcoma (PO) originates from the outer fibrous layer of the periosteum.[3] <br/>Parosteal osteosarcoma is typically a low-grade tumor (LG- PO) but may be associated with a high-grade component in 16–43% of cases, in which cases the tumor may be referred to as showing high-grade transformation, anaplastic change or dedifferentiation (DD-PO). The latter is the preferred terminology by The World Health Organization 2013 Classification of Tumors of Soft Tissue and Bone (WHO).[6] <br/>Compared with low-grade parosteal osteosarcoma, dedifferentiated parosteal osteosarcoma possesses a higher capability of distant metastasis in association with a poor clinical outcome.[5] <br/>60% of cases of parosteal osteosarcoma diagnosed in the third and fourth decades of life.<br/>The femur is the commonest site affected (approximately two-thirds of cases and usually in the distal metaphysis), followed by the humerus and tibia. These 3 locations are accounting for>90%of cases.[10] <br/>Diagnosis of parosteal osteosarcoma (PO) needs a high index of suspicion. All clinicoradiologically doubtful lesion needs to be biopsied to confirm the diagnosis.[16] <br/>The diagnosis of PO is made by combining the patient’s medical history, clinical symptoms, laboratory examination, and imaging analysis with histopathological examination of the lesion after taking a biopsy.(16) <br/>Parosteal osteosarcoma is one of the most frequently misdiagnosed entities in bone and soft-tissue tumors.<br/>It must be differentiated from other bone-forming lesions arising from the cortical surface like osteochondroma or myositis ossificans.<br/>Parosteal osteosarcoma has a limited Potentials for distant spread. Hence, surgical resection with adequate margins is the treatment of choice.[30]<br/>There is no role for systemic chemotherapy except in presence of dedifferentiation.<br/>Classic parosteal osteosarcoma has excellent survival rate with average five-year survival rate is about 90%.<br/>Dedifferentiated parosteal osteosarcoma confers worse prognosis of parosteal osteosarcoma and decreases the overall survival rate to be equal to conventional high-grade osteosarcoma. [39]<br/><br/> |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | السرطان العظمي الجارسمحاقى هي نوع فرعي جيد التمايز من السرطان العظمي حيث يتميز بنمو بطيء وورم خبيث منخفض الدرجة مع ميل بسيط للانتشار.<br/>السرطان العظمي الجارسمحاقى هي النوع الأكثر شيوعًا من السرطانات العظمية التي تظهر على سمحاق العظام وتمثل 2٪ -4٪ من جميع أورام العظام الخبيثة الأولية، وحوالي 4٪ -6٪ من جميع ساركوما العظام، و70٪ من ساركوما العظام السطحية.<br/>السرطان العظمي الجارسمحاقى ينشأ من الطبقة الليفية الخارجية من السمحاق. <br/>السرطان العظمى الجارسمحاقى هو عادة ورم منخفض الدرجة لكن قد يكون مصاحبا معه ورم عالي الدرجة في حوالي 16-43 % من الحالات وفى هذه الأثناء يسمى ورم عظمى جارسمحاقى ذو تحول عالي أو سرطان عظمى كشمي ,أو سرطان عظمى جارسمحاقى عديم التمايز وهذا هو الاسم المفضل لمنظمة الصحة العالمية حسب تصنيف منظمة الصحة لأورام الجهاز الحركي عام 2013<br/>مقارنة بمرض السرطان العظمى الجارسمحاقى قليل درجة الورم فان مرض سرطان عظمى جارسمحاقى عديم التمايز عنده قابلية أعلى لإرسال ثانويات سرطانية في أجزاء بعيده من الجسم وعادة تكون له نتائج سريرية سيئة.<br/>60%من حالات السرطان العظمى الجارسمحاقى يتم تشخيصهم في العقد الثالث أو الرابع من العمر وتمثل عظمة الفخذ حوالي 60% من الحالات يليها عظمة العضد وعظمة الساق. هذه الأماكن الثلاثة تمثل أكثر من 90%من الحالات.<br/>ان تشخيص مرض السرطان العظمى الجارسمحاقى يحتاج لدرجة عالية من التوقع الإكلينيكي، كما أنه يحتاج لتجميع المعلومات الإكلينيكية والأشعات الخاصة بالمرض وأحذ عينه من الورم لتحليلها وتحديد نوع الورم.<br/>ان مرض السرطان العظمى الجارسمحاقى من الأمراض التي يساء تشخيصها ولذلك يجب أن تفرق في تشخيصها بين الأورام التي تظهر على سطح العظم أو أي افات أخرى تظهر على سطح العظم مثل الورم العظمي الغضروفي الحميد أو الالتهابات العضلية العظمية.<br/> |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Issues CD | Issues also as CD. |
| 546 ## - LANGUAGE NOTE | |
| Text Language | Text in English and abstract in Arabic & English. |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Bones |
| Source of heading or term | qrmak |
| 653 #0 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Oncological Osteosarcoma Treated by Procedure |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ashraf Elnahal |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Walid Atef Ebeid |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wesam Abousenna |
| Relator term | thesis advisor. |
| 900 ## - Thesis Information | |
| Grant date | 01-01-2023 |
| Supervisory body | Ashraf Elnahal |
| -- | Walid Atef Ebeid |
| -- | Wesam Abousenna |
| Universities | Cairo University |
| Faculties | Faculty of Medicine |
| Department | Department of Orthopaedic Surgery |
| 905 ## - Cataloger and Reviser Names | |
| Cataloger Name | Aya Mohamed |
| Reviser Names | Huda |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Edition | 21 |
| Suppress in OPAC | No |
| Source of classification or shelving scheme | Home library | Current library | Date acquired | Inventory number | Full call number | Barcode | Date last seen | Effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 27.01.2025 | 90035 | Cai01.11.25.Ph.D.2023.Ho.F | 01010110090035000 | 27.01.2025 | 27.01.2025 | Thesis |