Impact of RAGE gene polymorphism in patients with type 2 diabetes complicated with diabetic nephropathy / (Record no. 172013)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 04685namaa22004451i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - أخر تعامل مع التسجيلة | |
| control field | 20250522111955.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250511s2024 ua a|||fr|m|| 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloguing agency | EG-GICUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GICUC |
| Modifying agency | EG-GICUC |
| Description conventions | rda |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| Language code of summary or abstract | eng |
| -- | ara |
| 049 ## - Acquisition Source | |
| Acquisition Source | Deposit |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 616.466 |
| 092 ## - LOCALLY ASSIGNED DEWEY CALL NUMBER (OCLC) | |
| Classification number | 616.466 |
| Edition number | 21 |
| 097 ## - Degree | |
| Degree | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Local Call Number | Cai01.11.18.Ph.D.2024.Ma.I. |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Authority record control number or standard number | Manar Ahmed Abdel Aziz Mansi, |
| Preparation | preparation. |
| 245 10 - TITLE STATEMENT | |
| Title | Impact of RAGE gene polymorphism in patients with type 2 diabetes complicated with diabetic nephropathy / |
| Statement of responsibility, etc. | By Manar Ahmed Abdel Aziz Mansi; Under Supervision of Prof. Dr. Hala Essam Eldin Mohamed Kahla, Prof. Dr. Aamal Ahmed Mohamed, Dr. Rasha Sobh Mohamed, Dr. Yasmin Abdel Fattah Mohamed |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | مدى التحور الجيني لمستقبل المنتجات النهائية للجلكزة المتقدمة (RAGE) في مرضى النوع 2 من البول السكري، وأثره على اعتلال الكلى السكري / |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 2024. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 92 pages : |
| Other physical details | illustrations ; |
| Dimensions | 25 cm. + |
| Accompanying material | CD. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Source | rda content |
| 337 ## - MEDIA TYPE | |
| Media type term | Unmediated |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | volume |
| Source | rdacarrier |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D)-Cairo University, 2024. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Bibliography: pages 200-250. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The development of genetic biomarkers in different chronic diseases has <br/>focused on assisting in diagnosis and monitoring disease complications. <br/>Receptor for advanced glycated end products (RAGE) gene <br/>polymorphism has been implicated previously in type 2 diabetes mellitus <br/>pathophysiology and its complications, particularly diabetic nephropathy. <br/>Objective: To assess single nucleotide polymorphism (SNP) of RAGE <br/>gene at rs 1800625 (-429 T> C) among type 2 diabetic patients and to <br/>investigate the relationship between this polymorphism and diabetic <br/>nephropathy. <br/>Methods: In a case control analytical study including 370 subjects; 185 <br/>T2DM patients complicated with nephropathy and 185 T2DM patients <br/>without nephropathy as control subjects. All T2DM patients were <br/>subjected to assessment of nephropathy according to ACR, serum <br/>creatinine and e-GFR and assessment of gene polymorphism at rs <br/>1800625 (-429T > C). <br/>Outcome measures: to assess the relation between RAGE gene <br/>polymorphism and Diabetic nephropathy in T2DM. <br/>Results: there was no significant difference between the 2 groups of our <br/>study (T2DM with and without nephropathy) regarding Allelic <br/>discrimination of RAGE gene at rs 1800625 (-429T > C). Also, there <br/>was no statistically significant relation between ACR, e-GFR, serum <br/>creatinine, FBS, HBA1C and allelic discrimination of RAGE gene at <br/>rs1800625 -429 T > C. <br/>Conclusion: There was no association between rage gene polymorphism <br/>at rs 1800625 (-429T > C) and diabetic nephropathy in type 2 diabetes <br/>mellitus. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | الهدف من هذه الدراسة هو الكشف عن تعدد أشكال أحادي النوكليوتيداتSNP)) في جين RAGE عند rs1800624 في مرضى السكري من النوع 2 وعلاقته باعتلال الكلى السكري. أجريت دراسة الحالة والشواهد هذه على 370 مريضًا بالسكري من النوع 2 مصاب أو غير مصاب باعتلال الكلى السكري (185 مريضا في كل مجموعة).<br/>النتائج: لم يكن هناك فرق كبير بين مجموعتين من دراستنا (T2DM مصاب أو غير مصاب باعتلال الكلى) من حيث تعدد الأشكال لجين الـ RAGE عند rs 1800625 (-429T>C).<br/>وعليه استنتجنا أنه لا يوجد ارتباط بين تعدد أشكال جين الـRAGE عند rs 1800625 -429T>C واعتلال الكلى السكري في داء السكري من النوع 2.<br/> |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Issues CD | Issued also as CD |
| 546 ## - LANGUAGE NOTE | |
| Text Language | Text in English and abstract in Arabic & English. |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | diabetic |
| Source of heading or term | qrmak |
| 653 #0 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Receptor for advanced glycated end products (RAGE) |
| -- | Gene polymorphism |
| -- | Type 2 diabetes mellitus (T2DM) |
| -- | Single nucleotide polymorphism (SNP) |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hala Essam Eldin Mohamed Kahla |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Aamal Ahmed Mohamed |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rasha Sobh Mohamed |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yasmin Abdel Fattah Mohamed |
| Relator term | thesis advisor. |
| 900 ## - Thesis Information | |
| Grant date | 01-01-2024 |
| Supervisory body | Hala Essam Eldin Mohamed Kahla |
| -- | Aamal Ahmed Mohamed |
| -- | Rasha Sobh Mohamed |
| -- | Yasmin Abdel Fattah Mohamed |
| Universities | Cairo University |
| Faculties | Faculty of Medicine |
| Department | Department of Internal Medicine |
| 905 ## - Cataloger and Reviser Names | |
| Cataloger Name | Nourhan |
| Reviser Names | Eman Ghareb |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Edition | 21 |
| Suppress in OPAC | No |
| Source of classification or shelving scheme | Home library | Current library | Date acquired | Inventory number | Full call number | Barcode | Date last seen | Effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.05.2025 | 91107 | Cai01.11.18.Ph.D.2024.Ma.I. | 01010110091107000 | 11.05.2025 | 11.05.2025 | Thesis |