Synthesis of Certain Fused Thienopyrimidines of Biological Interest / (Record no. 2548)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 032710000a22003370004500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GICUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223024944.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 061029s2006 ua a f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GICUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GICUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | Eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.04.M.Sc.2006.As.S. |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Asmaa Elsayed Abdellatief Kassab |
| 245 10 - TITLE STATEMENT | |
| Title | Synthesis of Certain Fused Thienopyrimidines of Biological Interest / |
| Statement of responsibility, etc. | Asmaa Elsayed Abdellatief Kassab ; Supervised Bothaina Abdelfattah Mousa , Manal Mostafa Kandeel , Omneya Mahmoud Khalil |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تشييد بعض مشتقات الثينوبيريميدينات الملتحمة ذات الاهمية البيولوجية |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Asmaa Elsayed Abdellatief Kassab , |
| Date of publication, distribution, etc. | 2006 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 141P : |
| Other physical details | ill ; |
| Dimensions | 30cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty Of Pharmacy - Department Of Organic Chemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The thesis is prefaced by an account on the synthesis of cycloalkeno - thieno[2 , 3 - d]pyrimidin - 4 (3H) - ones and triazolocycloalkenothienopyrimidine derivativesIn addition , a survey covering the different biological activities of some cycloalkenothienopyrimidines and their fused systems is givenPreparation of the root compounds vizethyl 2 - aminocycloocteno - [b]thiophene - 3 - carboxylate (II) , ethyl 2 - (3 - substituted thioureido) cycloocte - no[b]thiophene - 3 - carboxylates (IIIa and b) , 3 - substituted - 2 - thioxo - 1H , 3H - cyc - loocteno[4 , 5]thieno[2 , 3 - d]pyrimidin - 4 - ones (IVa and b) and 3 - amino - 2 - substit - uted aminocycloocteno[4 , 5]thieno[2 , 3 - d]pyrimidin - 4 (3H) - ones (XIIa and b) is presentedScheme 1 is concerned with the interaction of the ortho amino ester II with isothiocyanates to furnish IIIa and bFurthermore , cyclization of the latter was accomplished smoothly in ethanol saturated with dry hydrogen chloride to give the 2 - mercaptothienopyrimidin - 4 (3H) - ones IVa and b which was alkylated using different alkyl halides (methyl iodide , ethyl iodide and allyl bromide) to afford Va - fs regards Scheme 2 , it involves the reaction of IVa and b with ethyl chloroacetate to give 2 - ethoxycarbonylmethylthio - 3 - substituted cyclooct - eno[4 , 5]thieno[2 , 3 - d]pyrimidin - 4 (3H) - ones (VIa and b) Reaction of the latter with hydrazine hydrate gave the corresponding hydrazide VIIa and bCondensation of VIIa and b with different aromatic ketones (acetophenone , 4 - chloroacetophenone , 4 - aminoacetophenone and 4 - hydroxyacetophenone) afforded the corresponding arylethylidene derivatives VIIIa - hThe reaction of VIIIa - h with acetic anhydride yielded 2 - (acetyloxyethynylthio) - 3 - substituted cycloocteno[4 , 5]thieno[2 , 3 - d]pyrimidin - 4 (3H) - ones (XIa and b) , instead of expected 1 , 3 , 4 - oxadiazoline derivativesIn addition , 3 - phenyl - |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Biological Interest |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Fused Thienopyrimidines |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bothaina Abd El Fattah Mousa , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Manal Mostafa Kandeel , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Omneya Mahmoud Khalil , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Amira |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Esam |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.04.M.Sc.2006.As.S. | 01010110046150000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.04.M.Sc.2006.As.S. | 01020110046150000 | 22.09.2023 | CD - Rom | 46150.CD |