A Biochemical Study of some Neurotransmitter Substances and Neuroprotecting Enzymes in Newborns with No Visible CongenitalAnomalies / (Record no. 4537)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 045860000a22003490004500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GICUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223025041.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 061102s2006 ua a f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GICUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GICUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | Eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.12.02.M.Sc.2006.Ah.B |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Ahmed Fawzy Abdelrazik |
| 245 12 - TITLE STATEMENT | |
| Title | A Biochemical Study of some Neurotransmitter Substances and Neuroprotecting Enzymes in Newborns with No Visible CongenitalAnomalies / |
| Statement of responsibility, etc. | Ahmed Fawzy Abdelrazik ; Supervised Hamdi Mahmoud Hassaneen , Salwa MohamedYossef , Mohamed Ali Eldesouky |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسة بيوكيميائية لبعض الناقلات العصبية و بعض الانزيمات الحامية للخلايا العصبية فى الاطفال حديثى الولادة و الذين يعانون من خلل فى النمو غير واضح الاسباب |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Ahmed Fawzy Abdelrazik , |
| Date of publication, distribution, etc. | 2006 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 197P : |
| Other physical details | ill ; |
| Dimensions | 30cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty Of Science - Department Of Biochemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | This work has been carried out to establish accurate , reliable and early recognition and diagnosis of enzymatic and biochemical changes in neurotransmitters and neuroprotecting enzymes in neonatal cord blood , amniotic fluid and maternal blood in idiopathic fetal growth retardationIntrauterine fetal growth retardation (IUGR) implies increased risk of morbidity and mortality of the newbornThirty and 42 Egyptian women who delivered infant weighing 1500gm {u2013} 2500gm (LBW) and more than 2500gm (AGA) , respectively , were studiedAmniotic fluid , umbilical cord blood and maternal venous blood samples are collected at delivery from cases in the Obstetrics and Gynecology Hospital of Ain Shams University and transported under cooling condition to laboratory were directly separated the blood and frozen the plasma , leucocytes which are separated and amniotic fluid samples until the time of analysisIt was found that during pregnancy complicated by IUGR , a significant decreasing of glucose level in plasma maternal , cord blood and amniotic fluids of LBW than AGA infantsHypoglycemia decrease rates of fetal growth as an adaption to inadequate nutrient mother supplyOur results indicated lower plasma albumin of malnourished newborns and their mothers than control groupsDeficient nutrition leads to growth retardationLowering levels of RNA , DNA , Protein / DNA ratios (cell size) and RNA / DNA ratios (cell mass) of investigated group (LBW) than in normal pregnancy (AGA) which all of these parameters good index of fetal organs maturityNeuroprotecting enzymes (GS and GDH) deficiency have etiological role in IUGRGlutamine synthetase acitivity in human IUGR condation may indicate reinduction of an enzyme used in early development , due to glutamine synthetase is involved in the recycling of synaptaclly released glutamate and GABA and in the detoxification of ammonia and may provide the cells with glutamine neede for proliferationGlutamine\\\\glutamate and their closely related metabolites play critical roles in numerous cell processesTheir designation as conditionally essential nutrients downplays their importance in rapidly growing and proliferating cellsIn the present study a significant proportion of pregnant women in Egypt have biochemical hypozincemiaThis hypozincemia responsible for fetal growth retardation in this populationOur study indicated that IUGR , with multiple pathologies coexist , it may be difficult to achieve beneficial results by testing a single interventionOn the basis of the evidence reviewed and our results only balanced protein / energy supplementation , trace element supplementation (especially zinc) and measuring all biochemical markers have potential beneficial effects on reducing the incidence of low birth IUGRIntrauterine growth retardation (IUGR) increases a risk of perinatal complications and may carry a negative influence on a later baby{u2019}s mental and physical development and so , some adult diseases may have their origins in uteroThis result offer to follow up studies of older children |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Cell Size |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | gestational |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Malnutrition |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hamdi Mahmoud Hassaneen , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Ali Eldesouky , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Salwa MohamedYossef , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Amira |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Mustafa |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type |
|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.12.02.M.Sc.2006.Ah.B | 01010110046185000 | 22.09.2023 | Thesis | |
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.12.02.M.Sc.2006.Ah.B | 01020110046185000 | 22.09.2023 | CD - Rom |