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A pharmaceutical study on improving the solubility & bioavailability of an antihistaminic drug / (Record no. 48148)

MARC details
000 -LEADER
fixed length control field 02395cam a2200349 a 4500
003 - CONTROL NUMBER IDENTIFIER
control field EG-GiCUC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250223031104.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 141110s2014 ua h f m 000 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency EG-GiCUC
Language of cataloging eng
Transcribing agency EG-GiCUC
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title eng
049 ## - LOCAL HOLDINGS (OCLC)
Holding library Deposite
097 ## - Thesis Degree
Thesis Level M.Sc
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
Classification number Cai01.08.08.M.Sc.2014.No.P
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Nolwa Gamal Ahmed Elsherif
245 12 - TITLE STATEMENT
Title A pharmaceutical study on improving the solubility & bioavailability of an antihistaminic drug /
Statement of responsibility, etc. Nolwa Gamal Ahmed Elsherif ; Supervised Soad Ali Yehia , Mohamed Shafik Elridy , Mina Ibrahim Tadros
246 15 - VARYING FORM OF TITLE
Title proper/short title دراسة صيدلية لتحسين الذوبان والاتاحة الحيوية لعقار مضاد للحساسية
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Cairo :
Name of publisher, distributor, etc. Nolwa Gamal Ahmed Elsherif ,
Date of publication, distribution, etc. 2014
300 ## - PHYSICAL DESCRIPTION
Extent 192 P. :
Other physical details facsimiles ;
Dimensions 25cm
502 ## - DISSERTATION NOTE
Dissertation note Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics
520 ## - SUMMARY, ETC.
Summary, etc. Fexofenadine, the active metabolite of the well-known and effective H1 receptor antagonist, terfenadine, is administered as the hydrochloride salt. Fexofenadine hydrochloride (FXD) is a non-sedating antihistamine that provides rapid, long-acting, and highly selective peripheral H1 receptor antagonist activity. It is used for allergic rhinitis and urticarial at a recommended oral dose of 30 to 180 mg. But it has a bitter taste, slightly soluble in water and having an oral bioavailability of 35%. The maximum plasma concentration is reached 2.6 hours (Tmax) post-dose. Various approaches have been applied to mask the taste and improve its solubility and bioavailability. Solid oral dosage forms represent the preferred class of products of the drugs that are administered orally. The tablets dosage form has a number of advantages. Tablets are unit dosage form that offers the greatest dose precision and the least content variability. Tablets are also the lowest in their cost, the easiest and cheapest to package
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE
Additional physical form available note Issued also as CD
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Amproving the solubility
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Antihistaminic drug
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Fexofenadine hydrochloride (FXD)
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Mina Ibrahim Tadros ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Mohamed Shafik Elridy ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Soad Ali Yehia ,
Relator term
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a>
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Aml
Reviser Cataloger
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Nazla
Reviser Revisor
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Koha item type Thesis
Holdings
Source of classification or shelving scheme Not for loan Home library Current library Date acquired Full call number Barcode Date last seen Koha item type Copy number
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة قاعة الرسائل الجامعية - الدور الاول 11.02.2024 Cai01.08.08.M.Sc.2014.No.P 01010110063858000 22.09.2023 Thesis  
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة مخـــزن الرســائل الجـــامعية - البدروم 11.02.2024 Cai01.08.08.M.Sc.2014.No.P 01020110063858000 22.09.2023 CD - Rom 63858.CD