A pharmaceutical study on improving the solubility & bioavailability of an antihistaminic drug / (Record no. 48148)
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000 -LEADER | |
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fixed length control field | 02395cam a2200349 a 4500 |
003 - CONTROL NUMBER IDENTIFIER | |
control field | EG-GiCUC |
005 - DATE AND TIME OF LATEST TRANSACTION | |
control field | 20250223031104.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
fixed length control field | 141110s2014 ua h f m 000 0 eng d |
040 ## - CATALOGING SOURCE | |
Original cataloging agency | EG-GiCUC |
Language of cataloging | eng |
Transcribing agency | EG-GiCUC |
041 0# - LANGUAGE CODE | |
Language code of text/sound track or separate title | eng |
049 ## - LOCAL HOLDINGS (OCLC) | |
Holding library | Deposite |
097 ## - Thesis Degree | |
Thesis Level | M.Sc |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
Classification number | Cai01.08.08.M.Sc.2014.No.P |
100 0# - MAIN ENTRY--PERSONAL NAME | |
Personal name | Nolwa Gamal Ahmed Elsherif |
245 12 - TITLE STATEMENT | |
Title | A pharmaceutical study on improving the solubility & bioavailability of an antihistaminic drug / |
Statement of responsibility, etc. | Nolwa Gamal Ahmed Elsherif ; Supervised Soad Ali Yehia , Mohamed Shafik Elridy , Mina Ibrahim Tadros |
246 15 - VARYING FORM OF TITLE | |
Title proper/short title | دراسة صيدلية لتحسين الذوبان والاتاحة الحيوية لعقار مضاد للحساسية |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Place of publication, distribution, etc. | Cairo : |
Name of publisher, distributor, etc. | Nolwa Gamal Ahmed Elsherif , |
Date of publication, distribution, etc. | 2014 |
300 ## - PHYSICAL DESCRIPTION | |
Extent | 192 P. : |
Other physical details | facsimiles ; |
Dimensions | 25cm |
502 ## - DISSERTATION NOTE | |
Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics |
520 ## - SUMMARY, ETC. | |
Summary, etc. | Fexofenadine, the active metabolite of the well-known and effective H1 receptor antagonist, terfenadine, is administered as the hydrochloride salt. Fexofenadine hydrochloride (FXD) is a non-sedating antihistamine that provides rapid, long-acting, and highly selective peripheral H1 receptor antagonist activity. It is used for allergic rhinitis and urticarial at a recommended oral dose of 30 to 180 mg. But it has a bitter taste, slightly soluble in water and having an oral bioavailability of 35%. The maximum plasma concentration is reached 2.6 hours (Tmax) post-dose. Various approaches have been applied to mask the taste and improve its solubility and bioavailability. Solid oral dosage forms represent the preferred class of products of the drugs that are administered orally. The tablets dosage form has a number of advantages. Tablets are unit dosage form that offers the greatest dose precision and the least content variability. Tablets are also the lowest in their cost, the easiest and cheapest to package |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
Additional physical form available note | Issued also as CD |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | Amproving the solubility |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | Antihistaminic drug |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | Fexofenadine hydrochloride (FXD) |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Mina Ibrahim Tadros , |
Relator term | |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Mohamed Shafik Elridy , |
Relator term | |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Soad Ali Yehia , |
Relator term | |
856 ## - ELECTRONIC LOCATION AND ACCESS | |
Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
Cataloger | Aml |
Reviser | Cataloger |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
Cataloger | Nazla |
Reviser | Revisor |
942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
Source of classification or shelving scheme | Dewey Decimal Classification |
Koha item type | Thesis |
Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
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Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.08.M.Sc.2014.No.P | 01010110063858000 | 22.09.2023 | Thesis | ||
Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.08.M.Sc.2014.No.P | 01020110063858000 | 22.09.2023 | CD - Rom | 63858.CD |