MARC details
000 -LEADER |
fixed length control field |
02260cam a2200301 a 4500 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
EG-GiCUC |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
141123s2014 ua d f m 000 0 eng d |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
EG-GiCUC |
Language of cataloging |
eng |
Transcribing agency |
EG-GiCUC |
041 0# - LANGUAGE CODE |
Language code of text/sound track or separate title |
eng |
049 ## - LOCAL HOLDINGS (OCLC) |
Holding library |
Deposite |
097 ## - Thesis Degree |
Thesis Level |
M.Sc |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
Classification number |
Cai01.12.10.M.Sc.2014.Sa.S |
100 0# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Salwa Magdy Ahmed Eldaly |
245 10 - TITLE STATEMENT |
Title |
Synthesis of some new heterocyclic compounds from available nitriles with expected biological activity / |
Statement of responsibility, etc. |
Salwa Magdy Ahmed Eldaly ; Sypervised Fathy M. Abdelrazek |
246 15 - VARYING FORM OF TITLE |
Title proper/short title |
"تشييد بعض المركبات غير متجانسة الحلقة الجديدة من نتيريلات متوافرة ذات نشاط بيولوجى متوقع" |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Place of publication, distribution, etc. |
Cairo : |
Name of publisher, distributor, etc. |
Salwa Magdy Ahmed Eldaly , |
Date of publication, distribution, etc. |
2014 |
300 ## - PHYSICAL DESCRIPTION |
Extent |
89 P. : |
Other physical details |
charts ; |
Dimensions |
25cm |
502 ## - DISSERTATION NOTE |
Dissertation note |
Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Organic Chemistry |
520 ## - SUMMARY, ETC. |
Summary, etc. |
The original work of this thesis includes the study of the reaction of 1- cyanoacetylpyrazole 1 with phenyl isothiocyanate followed by the addition of different halocarbonyl compounds to afford thiazole and oxathiepine derivatives and the reaction of the arylhydrazo derivative of this compound with phenylene-1,4-diamine to give the compounds 13. Refluxing of 13 with hydrazine hydrate afforded aminotriazoles 15. Compound 1 reacts with different arylazo derivatives of aminopyrazoles to afford the corresponding pyrazolo[1,5-a]pyrimidine derivatives. Compound 21 reacted with phenyl isothiocyanate followed by the addition of different halocarbonyl compounds, the N-alkylated derivatives 24 were obtained.The reaction of 1 with 4- aminoacetophenone afforded the cyanoacetamide derivative 26 which underwent different chemical reactions to give arylidines, iminochromenes, di-arylidenes, di- iminochromenes, di-arylazo compounds and di-thiazoles. The antitumor activity of some of the newly synthesized compounds was investigated in vitro besides Molecule rmodeling (using MOE 2008) |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
Additional physical form available note |
Issued also as CD |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
1-Cyanoacetylpyr azole |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Oxathiepines |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Thiazole |
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Fathy Mohamed Abdelrazek , |
Relator term |
|
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Aml |
Reviser |
Cataloger |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Nazla |
Reviser |
Revisor |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
Dewey Decimal Classification |
Koha item type |
Thesis |