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Synthesis of some new heterocyclic compounds from available nitriles with expected biological activity / (Record no. 48363)

MARC details
000 -LEADER
fixed length control field 02260cam a2200301 a 4500
003 - CONTROL NUMBER IDENTIFIER
control field EG-GiCUC
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 141123s2014 ua d f m 000 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency EG-GiCUC
Language of cataloging eng
Transcribing agency EG-GiCUC
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title eng
049 ## - LOCAL HOLDINGS (OCLC)
Holding library Deposite
097 ## - Thesis Degree
Thesis Level M.Sc
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
Classification number Cai01.12.10.M.Sc.2014.Sa.S
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Salwa Magdy Ahmed Eldaly
245 10 - TITLE STATEMENT
Title Synthesis of some new heterocyclic compounds from available nitriles with expected biological activity /
Statement of responsibility, etc. Salwa Magdy Ahmed Eldaly ; Sypervised Fathy M. Abdelrazek
246 15 - VARYING FORM OF TITLE
Title proper/short title "تشييد بعض المركبات غير متجانسة الحلقة الجديدة من نتيريلات متوافرة ذات نشاط بيولوجى متوقع"
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Cairo :
Name of publisher, distributor, etc. Salwa Magdy Ahmed Eldaly ,
Date of publication, distribution, etc. 2014
300 ## - PHYSICAL DESCRIPTION
Extent 89 P. :
Other physical details charts ;
Dimensions 25cm
502 ## - DISSERTATION NOTE
Dissertation note Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Organic Chemistry
520 ## - SUMMARY, ETC.
Summary, etc. The original work of this thesis includes the study of the reaction of 1- cyanoacetylpyrazole 1 with phenyl isothiocyanate followed by the addition of different halocarbonyl compounds to afford thiazole and oxathiepine derivatives and the reaction of the arylhydrazo derivative of this compound with phenylene-1,4-diamine to give the compounds 13. Refluxing of 13 with hydrazine hydrate afforded aminotriazoles 15. Compound 1 reacts with different arylazo derivatives of aminopyrazoles to afford the corresponding pyrazolo[1,5-a]pyrimidine derivatives. Compound 21 reacted with phenyl isothiocyanate followed by the addition of different halocarbonyl compounds, the N-alkylated derivatives 24 were obtained.The reaction of 1 with 4- aminoacetophenone afforded the cyanoacetamide derivative 26 which underwent different chemical reactions to give arylidines, iminochromenes, di-arylidenes, di- iminochromenes, di-arylazo compounds and di-thiazoles. The antitumor activity of some of the newly synthesized compounds was investigated in vitro besides Molecule rmodeling (using MOE 2008)
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE
Additional physical form available note Issued also as CD
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term 1-Cyanoacetylpyr azole
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Oxathiepines
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Thiazole
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Fathy Mohamed Abdelrazek ,
Relator term
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Aml
Reviser Cataloger
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Nazla
Reviser Revisor
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Koha item type Thesis
Holdings
Source of classification or shelving scheme Not for loan Home library Current library Date acquired Full call number Barcode Date last seen Koha item type Copy number
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة قاعة الرسائل الجامعية - الدور الاول 11.02.2024 Cai01.12.10.M.Sc.2014.Sa.S 01010110064013000 22.09.2023 Thesis  
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة مخـــزن الرســائل الجـــامعية - البدروم 11.02.2024 Cai01.12.10.M.Sc.2014.Sa.S 01020110064013000 22.09.2023 CD - Rom 64013.CD