Role of aberrant growth factor expression and cytochrome P2D6 polymorphism in endocrine resistance in breast cancer using the real time superarray technique / (Record no. 48906)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02317cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031126.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 141224s2014 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.19.04.Ph.D.2014.Ib.R |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Ibrahim Abdelaziz Ibrahim Malash |
| 245 10 - TITLE STATEMENT | |
| Title | Role of aberrant growth factor expression and cytochrome P2D6 polymorphism in endocrine resistance in breast cancer using the real time superarray technique / |
| Statement of responsibility, etc. | Ibrahim Abdelaziz Ibrahim Malash ; Supervised Rabab Mohamed Gaafar , Sabry Mohamed Shaarawy , Osman Mohamed Mansour |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسة آليات المقاومه للعلاج الهرمونى لدى مريضات سرطان الثدى و امكانية استحداث طرق جديده للعلاج |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Ibrahim Abdelaziz Ibrahim Malash , |
| Date of publication, distribution, etc. | 2014 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 138 P. : |
| Other physical details | charts ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Oncology - Medical |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | In an attempt to explore genetic factors behind resistance to tamoxifen and if possible targeting these factors or predicting response prior to therapy to avoid Tamoxifen in some patients who are expected to respond poorly to the drug. We prospectively studied the response to tamoxifen in braest cancer patients with measurable locally recurrent and / or metastatic hormone positive disease. We devided the patients into responsive and refractory groups according to response they showed to the drug. We studied the genetic profile of the groups to explore the effect of any genetc aberration that may be responsible for the degree of response to tamoxifen. Results showed that there is a statistically significant correlation between CYP2D6 mutations and resistance to tamoxifen P value = < 0.02 |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Breast cancer |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | CYP2D6 and gene profiling |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Hormone resistance |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Osman Mohamed Mansour , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rabab Mohamed Gaafar , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sabry Mohamed Shaarawy , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.19.04.Ph.D.2014.Ib.R | 01010110064297000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.19.04.Ph.D.2014.Ib.R | 01020110064297000 | 22.09.2023 | CD - Rom | 64297.CD |