Effect of Ý {u2013} glucan and Ü- lipoic acid in treatment of methylmercury - induced neurotoxicity in rats / (Record no. 48910)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02408cam a2200313 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 141224s2014 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.09.M.Sc.2014.Yo.E |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Yosra Assem Hussien |
| 245 10 - TITLE STATEMENT | |
| Title | Effect of Ý {u2013} glucan and Ü- lipoic acid in treatment of methylmercury - induced neurotoxicity in rats / |
| Statement of responsibility, etc. | Yosra Assem Hussien ; Supervised Ezz Eldin Eldenshary , Somaia Ahmed Nada |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تأثير البتاجلوكان و حمض الالفاليبويك فى علاج السمية العصبية الناتجة عن ميثيل الزئبق فى الجرذان |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Yosra Assem Hussien , |
| Date of publication, distribution, etc. | 2014 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 164 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Neurotoxicity is one the most common cause of many neurodegenerative diseases. One of the best known neurotoxicants is methylmercury (MeHg), a ubiquitous environmental toxicant that leads to neurological and developmental deficits in animals and humans. Impairment in intracellular calcium homeostasis, alteration of glutamate homeostasis and oxidative stress are considered as important events in MeHg - induced neurotoxicity. Neurotoxicity was induced in rats by oral methylmercuric chloride (MMC) in dose (3 mg / kg, p.o) for fifteen days. Alpha lipoic acid (60 mg / kg p.o) and Ý - glucan (100 and 200 mg / kg, p.o) either alone or in combination were adminstered orally to investigate their therapeutic effects on MMC - induced neurotoxicity. Behavioral changes were evaluated by using activity cage and rotarod methods as well as oxidative stress biochemical parameters for detection of glutathione (GSH), malondialdehyde (MDA), nitric oxide (NO) levels and superoxide dismutase (SOD) activity were analyzed in brain homogenates. Assessment of brain neurotransmitters (glutamate and GABA) in the cortex and hippocampus of neurotoxic rats |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Activity cage |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Neurotoxicity |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Rotarod |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ezz Eldin Eldenshary , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Somaia Ahmed Nada , |
| Relator term | |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.09.M.Sc.2014.Yo.E | 01010110064302000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.09.M.Sc.2014.Yo.E | 01020110064302000 | 22.09.2023 | CD - Rom | 64302.CD |