LAPTM4B : (Record no. 50124)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02470cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031204.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 150329s2014 ua f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.03.Ph.D.2014.Ma.L |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Marwa Ahmed Ali Mohammed Ali Elgebeli |
| 245 10 - TITLE STATEMENT | |
| Title | LAPTM4B : |
| Remainder of title | A novel biomarker for hepatocellular carcinoma / |
| Statement of responsibility, etc. | Marwa Ahmed Ali Mohammed Ali Elgebeli ; Supervised Olfat Gamil Shaker , Yasser Hussein Nassar , Amr Aly Zahra |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دلاله كيميائيه جديده لسرطان الكبد LAPTM4B |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Marwa Ahmed Ali Mohammed Ali Elgebeli , |
| Date of publication, distribution, etc. | 2014 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 97 P. ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Medical Biochemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Liver cancer is the fifth most common cancer worldwide and the third most deadly. This study aimed to explore the association of LAPTM4B gene polymorphism with HCC in Egyptian patients and whether this genetic polymorphism is associated with the clinicopathological characteristics of the disease. The study included 70 patients with hepatocellular carcinoma. And 50 healthy subjects serving as control. Physical and clinical examinations were done to all subjects. 10 ml of blood were collected from each subject. The following was done; Liver function tests, CBC, DNA extraction from whole blood, genotyping of LAPTM4B gene by PCR, agarose gel electrophoresis and quantitation of protein level of LAPTM4B by ELISA. LAPTM4B *2 / 2 was associated with a significant increased risk of HCC compared with LAPTM4B*1 / 1 (p = 0.006). It is also found that the frequency of allele *2 was higher in HCC (47.9%) than in controls [p < .05]. There was higher level of LAPTM4B protein among HCC patients genotype 2* / 2* (1680.82 ± 654.89) than those have genotype 1* / 2* (1216.25 ± 650.89) and 1*/1* (1144.80 ± 659.98). There was significant Association of LAPTM4B genotypes, protein level in HCC patients and TNM staging |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | HCC |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | LAPTM4B |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Polymorphism |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Amr Aly Zahra , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Olfat Gamil Shaker , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yasser Hussein Nassar , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.03.Ph.D.2014.Ma.L | 01010110064936000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.03.Ph.D.2014.Ma.L | 01020110064936000 | 22.09.2023 | CD - Rom | 64936.CD |