MARC details
000 -LEADER |
fixed length control field |
02610cam a2200325 a 4500 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
EG-GiCUC |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
150331s2014 ua dh f m 000 0 eng d |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
EG-GiCUC |
Language of cataloging |
eng |
Transcribing agency |
EG-GiCUC |
041 0# - LANGUAGE CODE |
Language code of text/sound track or separate title |
eng |
049 ## - LOCAL HOLDINGS (OCLC) |
Holding library |
Deposite |
097 ## - Thesis Degree |
Thesis Level |
M.Sc |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
Classification number |
Cai01.11.18.M.Sc.2014.Ah.D |
100 0# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Ahmed Atef Fouad Mekky |
245 10 - TITLE STATEMENT |
Title |
Desensitization of donor specific resistant positive lymphocyte cross-match by donor specific mesenchymal stem cell transfusion / |
Statement of responsibility, etc. |
Ahmed Atef Fouad Mekky ; Supervised Mohammed Gamal Aldin Saadi , May Abdelmonem Hasab Allah , Mervat Mohammed Saad Elansary |
246 15 - VARYING FORM OF TITLE |
Title proper/short title |
إزالة التحسس بإنهاء التفاعل التطابقى الإيجابى للخلايا الليمفاوية بخلايا المتبرع الجزعية |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Place of publication, distribution, etc. |
Cairo : |
Name of publisher, distributor, etc. |
Ahmed Atef Fouad Mekky , |
Date of publication, distribution, etc. |
2014 |
300 ## - PHYSICAL DESCRIPTION |
Extent |
138 P. : |
Other physical details |
charts , facsimiles ; |
Dimensions |
25cm |
502 ## - DISSERTATION NOTE |
Dissertation note |
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Internal Medicine |
520 ## - SUMMARY, ETC. |
Summary, etc. |
Background: Donor specific antibodies (DSA) and a positive cross-match in patients who are sensitized through previous blood transfusions, organ transplantation or pregnancy are an important obstacle in kidney transplantation. , trials of allograft transplantation across the HLA barrier have employed desensitization strategies, including the use of plasmapheresis, intravenous immunoglobulins, anti-B-cell monoclonal antibodies and splenectomy, associated with high-intensity immunosuppressive regimens. These measures have proven only partially successful in preventing or treating humoral rejection in high-risk patients, while causing a significant increase in the risk of severe infectious complications occurring after transplantation. Mesenchymal stem cells (MSCs) have immunomodulatory capacity and are able to suppress allo-specific antibody production in vitro, and may therefore help overcome a positive cross-match in sensitized transplant recipients. Aim of the Work: To evaluate the effect of mesenchymal stem cell transfusion on desensitization of donor specific resistant positive lymphocyte cross-match and /or high titre Panel Reactive Antibody (PRA) |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
Additional physical form available note |
Issued also as CD |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Desensitisation protocols |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Immunomodulatory properties |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Mesenchymal stem cells |
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
May Abdelmonem Hasab Allah , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Mervat Mohammed Saad El Ansary , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Mohammed Gamal Aldin Saadi , |
Relator term |
|
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Nazla |
Reviser |
Revisor |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Soheir |
Reviser |
Cataloger |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
Dewey Decimal Classification |
Koha item type |
Thesis |