Insulin - like growth factor 1 and interleukin- 6- as key cytokines in pathogenesis of multiple myeloma / (Record no. 50570)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02558cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031218.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 150422s2014 ua h f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.12.02.M.Sc.2014.Ma.I |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Magda Erian Saied |
| 245 10 - TITLE STATEMENT | |
| Title | Insulin - like growth factor 1 and interleukin- 6- as key cytokines in pathogenesis of multiple myeloma / |
| Statement of responsibility, etc. | Magda Erian Saied ; Supervised Mohamed Kamal Ahmed , Olfat Gameel Shaker , Mohamed Ali Eldesouky |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | عامل النمو مشابه الانسولين 1 و عامل انترلوكين-6 كسيتو كينز رئيسى فى تطور مرضى الميلوما المتعددة |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Magda Erian Saied , |
| Date of publication, distribution, etc. | 2014 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 128 P. : |
| Other physical details | facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Biochemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Multiple myeloma is a malignant neoplasm of plasma cells that commonly results in overproduction of large amounts of monoclonal immunoglobulin. Insulin like growth Factor1 (IGF1) andinterleukin- 6 (IL6) promote the proliferation and survival of myeloma cells. The present work is intended to study IGF- 1 and IL- 6 as key cytokines and prognostic biomarkers in Egyptian multiple myeloma patients to help in defining the biological profile and hence additional therapeutic lines for the disease. This study includes 40 newly diagnosed multiple mMyeloma patients (29 males and 11females) their age range from 35 - 70 years and 20 healthy controls matching in ages and sex. The enrolled patients were referred to Kasr Elaini centre of clinical oncology and radiation Cairo university. ELISA technique was used to measure IGF- 1 and IL- 6 in subjects{u2019} sera. Patients were included in the survival analysis after induction therapy with both steroids and thalidomide. IGF- 1 and IL- 6 were measured by ELISA before and after treatment. This study showed that IGF- 1 and IL- 6 after treatment lower than before treatment but IGF-1 level was more significantly responding to treatment with Pvalue 0.001 |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | IGF- 1 |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | IL- 6 |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | MM |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Ali Eldesouky , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Kamal Ahmed , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Olfat Gameel Shaker , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.12.02.M.Sc.2014.Ma.I | 01010110065240000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.12.02.M.Sc.2014.Ma.I | 01020110065240000 | 22.09.2023 | CD - Rom | 65240.CD |