Histological assessment of the efficiency of grape seed extract on doxorubicin-induced cardiotoxicity in adult male albino rats / (Record no. 50909)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02989cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031227.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 150514s2014 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.16.M.Sc.2014.Fa.H |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Fatma Alzahraa Mohamed Helmy |
| 245 10 - TITLE STATEMENT | |
| Title | Histological assessment of the efficiency of grape seed extract on doxorubicin-induced cardiotoxicity in adult male albino rats / |
| Statement of responsibility, etc. | Fatma Al-Zahraa Mohamed Helmy ; Supervised Samiha Aly Mortada , Dalia Fathy El-deeb , Zeinab Mohamed El maadawi |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | التقييم الهستولوجي لفاعلية مستخلص بذور العنب على تسمم القلب المستحدث بعقار دوكسوروبيسين فى ذكور الجرذان البيضاء البالغة |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Fatma Alzahraa Mohamed Helmy , |
| Date of publication, distribution, etc. | 2014 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 165 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Histology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Thirty adult male albino rats were included in this study.They were divided into four groups: Group I (control group) included 9 rats .Group II (GSE treated group): 7rats were given 100mg/kg GSE dissolved in 0.5 ml distilled water orally for 12 days. Group III (DOXO treated group): 7rats were injected intraperitonial with 20mg/kg DOXO on day 7 from the start of the experiment. Group IV (GSE and DOXO treated group): 7rats were given GSE as in Group II for 12days and on the 7th day, a single dose of DOXO was injected with the same dose and route as in Group III. All rats were sacrificed on day 13. Myocardial sections were stained with H&E, Masson{u2019}s trichrome and immunohistochemical stain for Bcl-2. The mean area percent of collagen fibers and immunoreactivity of Bcl-2 were measured. Other myocardial specimens were prepared for electron microscopic examination.Results: Group I and II revealed similar histological architecture of the myocardium on light and electron microscopic examination and a non significant difference in the mean area % of collagen fibers and Bcl-2 immunoreaction. Group III myocardial sections stained with H&E revealed disorganized, disrupted and degenerated cardiac muscle fibers that exhibited homogenous acidophilic sarcoplasm with loss of cross striations, sarcoplasmic vacculations, pyknotic nuclei with congested, dilated blood capillaries, RBCs extravasations, fibroblast proliferation and inflammatory cellular infiltration inbetween |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Cardiotoxicity |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Doxorubicin |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Grape seed extract |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dalia Fathy El-deeb , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Samiha Aly Mortada , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zeinab Mohamed Elmaadawi , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Enas |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.16.M.Sc.2014.Fa.H | 01010110065408000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.16.M.Sc.2014.Fa.H | 01020110065408000 | 22.09.2023 | CD - Rom | 65408.CD |