MARC details
| 000 -LEADER |
|---|
| fixed length control field |
02451cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
150521s2014 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
EG-GiCUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GiCUC |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 049 ## - LOCAL HOLDINGS (OCLC) |
|---|
| Holding library |
Deposite |
| 097 ## - Thesis Degree |
|---|
| Thesis Level |
Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
|---|
| Classification number |
Cai01.10.04.Ph.D.2014.Hu.M |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Huda Omar Abubaker |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Molecular and biochemical studies on osteoarthritis in equine/ |
| Statement of responsibility, etc. |
Huda Omar Abubaker ; Supervised Hatim Mohamed Ahmed Elhindi , Said Zaki Mousa , Adel M. Abouelfetouh Elbehairy |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
دراسات جزيئية وبيوكيميائية على الالتهاب العظمى المفصلى فى الخيول |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Cairo : |
| Name of publisher, distributor, etc. |
Huda Omar Abubaker , |
| Date of publication, distribution, etc. |
2014 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
239 P. : |
| Other physical details |
charts , facsimiles ; |
| Dimensions |
25cm |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Thesis (Ph.D.) - Cairo University - Faculty of Veterinary Medicine - Department of Biochemistry and Chemistry of Nutrition |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
A central feature of the osteoarthritis (OA) involves erosive destruction of the articular cartilage extracellular matrix (ECM) on the surfaces of joints. The resultant loss of joint function makes studies on mechanisms underlying ECM degradation critical for treatment of the disease and prevention of disability. In the present study serum and synovial fluid samples were collected from normal (n=20), Early OA (n=10) and Late OA (n=20) adult male horses attended from surgery clinic, faculty of veterinary medicine Cairo University. The concentrations of total (TGAGs), individual (CS) and non sulphated (HA) glycosaminoglycans, Procollagen IIC-propeptide (PIICP) and Tartarate resistant acid phosphatase(TRAP) activities were estimated in serum and synovial fluid .The activities of different types of matrix metalloproteinases (MMPs) and tissue inhibitor metalloproteinases (TIMPs) in synovial fluid were estimated by Substrate and Reverse zymography respectively and the expression of MMP-13 was determined by Western blot. The allele and genotype frequencies of the Growth differentiation factor 5(GDF5) and Asporin (ASPN) genes were estimated by PCR- SSCP |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
|---|
| Additional physical form available note |
Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
ECM |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
GAGs |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Osteoarthritis |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Adel Mohamed Abouelfetouh Elbehairy , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Hatim Mohamed Ahmed Elhindi , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Said Zaki Mousa , |
| Relator term |
|
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Nazla |
| Reviser |
Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Soheir |
| Reviser |
Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |
