MARC details
000 -LEADER |
fixed length control field |
02283cam a2200325 a 4500 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
EG-GiCUC |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
150526s2014 ua d f m 000 0 eng d |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
EG-GiCUC |
Language of cataloging |
eng |
Transcribing agency |
EG-GiCUC |
041 0# - LANGUAGE CODE |
Language code of text/sound track or separate title |
eng |
049 ## - LOCAL HOLDINGS (OCLC) |
Holding library |
Deposite |
097 ## - Thesis Degree |
Thesis Level |
M.Sc |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
Classification number |
Cai01.12.04.M.Sc.2014.Do.B |
100 0# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Doaa Galal Amin Mahmoud |
245 10 - TITLE STATEMENT |
Title |
Biophysical studies of melanin nanoparticles as radioprotectors / |
Statement of responsibility, etc. |
Doaa Galal Amin Mahmoud ; Supervised Reem Elgebaly , Monira Rageh , Hoda Abo-Shady |
246 15 - VARYING FORM OF TITLE |
Title proper/short title |
دراسات بيوفيزيائية للميلانين المحضر بتكنولوجيا النانو كماده حاميه من الإشعاع |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Place of publication, distribution, etc. |
Cairo : |
Name of publisher, distributor, etc. |
Doaa Galal Amin Mahmoud , |
Date of publication, distribution, etc. |
2014 |
300 ## - PHYSICAL DESCRIPTION |
Extent |
74 P. : |
Other physical details |
charts ; |
Dimensions |
25cm |
502 ## - DISSERTATION NOTE |
Dissertation note |
Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Biophysics |
520 ## - SUMMARY, ETC. |
Summary, etc. |
During radiotherapy, ionizing irradiation interacts with biological systems to produce free radicals, which attack various cellular components. The hematopoietic system is easily recognized to be radiosensitive and its damage may be severe. Melanin nanoparticles (MNPs) act as free radical scavengers prepared by polymerization of dopamine. In this study a total of 110 male BALB/C mice were divided into five equal groups. Each group contained 22 mice. Mice of group A did not receive MNPs or irradiation (control group), group B was injected intraperitoneally (i.p.) with 50 mg/kg MNPs. Mice of group C and D were exposed to a dose of 7 Gy {u0263}-irradiation and injected with the same dose of MNPs as in group B either 30 min pre- or post-irradiation, and group E was exposed to a dose of 7 Gy {u0263}-irradiation only. The impact of MNPs on peripheral blood, spleen and DNA damage induced by irradiation was evaluated by blood count, histopathology of the spleen and comet assay for the DNA in the bone marrow at 1, 4, 8 and 12 days post-irradiation |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
Additional physical form available note |
Issued also as CD |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Melanin nanoparticles |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Radioprotectors |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Radiotherapy |
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Hoda Aboshady , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Monira Rageh , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Reem Elgebaly , |
Relator term |
|
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Aml |
Reviser |
Cataloger |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Nazla |
Reviser |
Revisor |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
Dewey Decimal Classification |
Koha item type |
Thesis |