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Biophysical studies of melanin nanoparticles as radioprotectors / (Record no. 51047)

MARC details
000 -LEADER
fixed length control field 02283cam a2200325 a 4500
003 - CONTROL NUMBER IDENTIFIER
control field EG-GiCUC
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 150526s2014 ua d f m 000 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency EG-GiCUC
Language of cataloging eng
Transcribing agency EG-GiCUC
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title eng
049 ## - LOCAL HOLDINGS (OCLC)
Holding library Deposite
097 ## - Thesis Degree
Thesis Level M.Sc
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
Classification number Cai01.12.04.M.Sc.2014.Do.B
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Doaa Galal Amin Mahmoud
245 10 - TITLE STATEMENT
Title Biophysical studies of melanin nanoparticles as radioprotectors /
Statement of responsibility, etc. Doaa Galal Amin Mahmoud ; Supervised Reem Elgebaly , Monira Rageh , Hoda Abo-Shady
246 15 - VARYING FORM OF TITLE
Title proper/short title دراسات بيوفيزيائية للميلانين المحضر بتكنولوجيا النانو كماده حاميه من الإشعاع
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Cairo :
Name of publisher, distributor, etc. Doaa Galal Amin Mahmoud ,
Date of publication, distribution, etc. 2014
300 ## - PHYSICAL DESCRIPTION
Extent 74 P. :
Other physical details charts ;
Dimensions 25cm
502 ## - DISSERTATION NOTE
Dissertation note Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Biophysics
520 ## - SUMMARY, ETC.
Summary, etc. During radiotherapy, ionizing irradiation interacts with biological systems to produce free radicals, which attack various cellular components. The hematopoietic system is easily recognized to be radiosensitive and its damage may be severe. Melanin nanoparticles (MNPs) act as free radical scavengers prepared by polymerization of dopamine. In this study a total of 110 male BALB/C mice were divided into five equal groups. Each group contained 22 mice. Mice of group A did not receive MNPs or irradiation (control group), group B was injected intraperitoneally (i.p.) with 50 mg/kg MNPs. Mice of group C and D were exposed to a dose of 7 Gy {u0263}-irradiation and injected with the same dose of MNPs as in group B either 30 min pre- or post-irradiation, and group E was exposed to a dose of 7 Gy {u0263}-irradiation only. The impact of MNPs on peripheral blood, spleen and DNA damage induced by irradiation was evaluated by blood count, histopathology of the spleen and comet assay for the DNA in the bone marrow at 1, 4, 8 and 12 days post-irradiation
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE
Additional physical form available note Issued also as CD
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Melanin nanoparticles
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Radioprotectors
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Radiotherapy
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Hoda Aboshady ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Monira Rageh ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Reem Elgebaly ,
Relator term
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Aml
Reviser Cataloger
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Nazla
Reviser Revisor
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Koha item type Thesis
Holdings
Source of classification or shelving scheme Not for loan Home library Current library Date acquired Full call number Barcode Date last seen Koha item type Copy number
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة قاعة الرسائل الجامعية - الدور الاول 11.02.2024 Cai01.12.04.M.Sc.2014.Do.B 01010110065746000 22.09.2023 Thesis  
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة مخـــزن الرســائل الجـــامعية - البدروم 11.02.2024 Cai01.12.04.M.Sc.2014.Do.B 01020110065746000 22.09.2023 CD - Rom 65746.CD