Studying the effect of cannabinoid receptor agonist and physostigmine on lps induced neuroinflammation and cognitive functions in male rats / (Record no. 51075)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 02674cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031232.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 150528s2014 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.16.M.Sc.2014.Ja.S |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Jackline Moawad Saad Allah Gaied |
| 245 10 - TITLE STATEMENT | |
| Title | Studying the effect of cannabinoid receptor agonist and physostigmine on lps induced neuroinflammation and cognitive functions in male rats / |
| Statement of responsibility, etc. | Jackline Moawad Saadallah Gaied ; Supervised Maha Mohamed Gamal , Wafaa Ibrahim Eleraky , Nivin Mahmoud Sharawy |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسة تأثير محفز مستقبلات الكانابينويد و الفيسوستيجمين على الالتهاب العصبى الناجم عن الليبوبولى سكاريد و على الوظائف الإدراكية فى ذكور الفئران |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Jackline Moawad Saad Allah Gaied , |
| Date of publication, distribution, etc. | 2014 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 200 P. : |
| Other physical details | charts ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine. - Department of Histology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Brain dysfunction is a common but not well-understood complication of sepsis. It often appears prior to the failure of other organs. Multiple factors could contribute to the development of acute brain dysfunction associated with sepsis including oxidative stress, proinflammatory mediators, endothelial activation and blood brain barrier disruption. In the present work, we aimed to test the beneficial anti-inflammatory and antioxidant properties of both 3-(1{u2032}1{u2032}-dimethylbutyl)-1-deoxy-x8-THC ( JWH 133), cannabinoid receptor (CB2R) agonist, and physostigmine (Esrine), cholinesterase enzyme inhibitor, on early LPS induced behavioural changes. In addition, the role of cholinergic and cannabinoid systems were also investigated on the LPS modulating effect on the p-glycoprotein, an ATP-driven drug efflux transporter, expression in the blood brain barrier (BBB). Rats were treated with a single intraperitoneal injection of lipopolysaccharide LPS (4 mg/kg) or vehicle. LPS treated rats were further subdivided in to 5 subgroups: None treated LPS and treated LPS with either saline, Eserine, JWH133 or Eserine+JWH133. |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Brain |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Cannabinoid |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Endotoxemia |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Maha Mohamed Gamal , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nivin Mahmoud Sharawy , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wafaa Ibrahim Eleraky , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Aml |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.16.M.Sc.2014.Ja.S | 01010110065758000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.16.M.Sc.2014.Ja.S | 01020110065758000 | 22.09.2023 | CD - Rom | 65758.CD |