MARC details
000 -LEADER |
fixed length control field |
03048cam a2200325 a 4500 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
EG-GiCUC |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
150706s2014 ua dh f m 000 0 eng d |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
EG-GiCUC |
Language of cataloging |
eng |
Transcribing agency |
EG-GiCUC |
041 0# - LANGUAGE CODE |
Language code of text/sound track or separate title |
eng |
049 ## - LOCAL HOLDINGS (OCLC) |
Holding library |
Deposite |
097 ## - Thesis Degree |
Thesis Level |
Ph.D |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
Classification number |
Cai01.11.28.Ph.D.2014.Kh.E |
100 0# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Khaled Tawfik Mohammed Tawfik |
245 10 - TITLE STATEMENT |
Title |
Endocrine complications in Thalassemia Intermedia / |
Statement of responsibility, etc. |
Khaled Tawfik Mohammed Tawfik ; Supervised Ahmed Maher Kaddah , Mostafa Zakaria Mohammed , Rania Ismail Magdy |
246 15 - VARYING FORM OF TITLE |
Title proper/short title |
مشاكل وظائف الغدد المختلفة في مرضي أنيميا البحر المتوسط المتوسطة |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Place of publication, distribution, etc. |
Cairo : |
Name of publisher, distributor, etc. |
Khaled Tawfik Mohammed Tawfik , |
Date of publication, distribution, etc. |
2014 |
300 ## - PHYSICAL DESCRIPTION |
Extent |
177 P. : |
Other physical details |
charts , facsimiles ; |
Dimensions |
25cm |
502 ## - DISSERTATION NOTE |
Dissertation note |
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pediatrics |
520 ## - SUMMARY, ETC. |
Summary, etc. |
Thalassemias are the most common genetic disorder on a worldwide basis. Ý-thalassemia is a severe hemolytic anemia which results from genetic defects in the synthesis of the hemoglobin Ý-chain. Various endocrine abnormalities have been described in patients with thalassemia major. Endocrine disturbances have also been observed in patients with thalassemia intermedia (TI). In this study endocrine functions were investigated in TI and here the frequency of different abnormalities is reported. Sixty patients (34 males, 26 females) with thalassemia intermedia, 11-18 years old (mean 13.98 yr) were studied. Medical history was obtained and a complete physical examination was done for each patient. The age, sex, age of initiation of blood transfusion and its regular or irregular administration, age of initiation of iron chelating agent and its compliance and serum ferritin levels were recorded using a questionnaire. Height, weight, sitting height and BMI were measured. Puberty was assessed using tanner staging system. OGTT, fasting, postprandial serum insulin, thyrotropin (TSH), free T4, total calcium, phosphorus, alkaline phosphatse and parathyroid hormone (PTH) were determined in these patients. The mean ± Standard Deviation (SD) serum ferritin level was 1501.7±524.16 og/L. Mean ± SD hemoglobin concentration was 7.4±1.22g/dl. Short stature was present in 46.7% of patients. Delayed puberty was present in 8.33% of patients, arrested puberty was observed in 15% of patients. Impaired glucose tolerance was observed in 11.66% and diabetes mellitus (DM) in 1.67% of patients. Hypothyroidism was observed in 23.33% of patients and only one patient (1.67%) had primary hypothyroidism. Hypoparathyroidism was found in one patient (1.67%) |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
Additional physical form available note |
Issued also as CD |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Endocrine complications |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Pediatrics |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Thalassemia Intermedia |
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Ahmed Maher Kaddah , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Mostafa Zakaria Mohammed , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Rania Ismail Magdy , |
Relator term |
|
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Nazla |
Reviser |
Revisor |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Soheir |
Reviser |
Cataloger |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
Dewey Decimal Classification |
Koha item type |
Thesis |