Prevalence and role of efflux pump activity in bacterial isolates of Enterobacteriaceae strains / (Record no. 51659)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02669cam a2200337 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031248.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 150721s2014 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.12.05.M.Sc.2014.Sa.P |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Sara Hussein Mohamed Abdou |
| 245 10 - TITLE STATEMENT | |
| Title | Prevalence and role of efflux pump activity in bacterial isolates of Enterobacteriaceae strains / |
| Statement of responsibility, etc. | Sara Hussein Mohamed Abdou ; Supervised Mary Sobhy Khalil , Rasha Hamed Elsherif |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | انتشار و دور نشاط المضخات الطاردة فى العزلات البكتيرية لسلالات الامعائيات |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Sara Hussein Mohamed Abdou , |
| Date of publication, distribution, etc. | 2014 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 166 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Botany-Microbiology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Active efflux of antimicrobial agents is a primary mechanism by which bacterial pathogens can become multidrug resistant. The combined use of efflux pump inhibitors (EPIs) with pump substrates is under exploration to overcome efflux-mediated multidrug resistance. Phenylalanine-arginine Ý-naphthylamide (PAÝN) is a well-studied EPI that is routinely combined with fluoroquinolone antibiotics, but few studies have assessed its utility in combination with Ý-lactam antibiotics. MICs of 219 unrepeated ESBL-positive ciprofloxacin resistance Enterobactereacae isolates isolated from various clinical samples from Kasr El-Einy Hospital. The prevalence of the efflux pump genes oqxAB and plasmid mediated Quinolones resistance qnrA , qnrB, qnrS, aac(6{u2019})-Ib and qepA in a total of 33 clinical isolates which show reduction in MIC after addition of PAÝN was investigated by PCR amplification. The study indicates the necessity for the detection of overexpressing efflux pumps at diagnostic level at least in tertiary care hospitals. Extended-spectrum Ý-lactamase-producing Escherichia coli (ESBL-EC) pose a serious threat to the successful treatment of common bacterial infections. Over the past two decades, there has been an increase in the prevalence of ESBL-EC |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Efflux pump activity in bacteria |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | ESBL (Extended-spectrum Ý-lactamase) |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Inhibitor PAÝN (Phenylalanine-arginine Ý- naphthylamide) |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mary Sobhy Khalil , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rasha Hamed Elsherif , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Enas |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.12.05.M.Sc.2014.Sa.P | 01010110066033000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.12.05.M.Sc.2014.Sa.P | 01020110066033000 | 22.09.2023 | CD - Rom | 66033.CD |