MARC details
| 000 -LEADER |
|---|
| fixed length control field |
02655cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
150801s2014 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
EG-GiCUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GiCUC |
| 041 0# - LANGUAGE CODE |
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| Language code of text/sound track or separate title |
eng |
| 049 ## - LOCAL HOLDINGS (OCLC) |
|---|
| Holding library |
Deposite |
| 097 ## - Thesis Degree |
|---|
| Thesis Level |
Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
|---|
| Classification number |
Cai01.11.07.Ph.D.2014.Wa.R |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Wafaa Mohamed Abdelghany Hassen |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Relationship between endothelial cell protein C receptor gene 6936 A / G and 4678 G / C polymorphisms and deep venous thrombosis / |
| Statement of responsibility, etc. |
Wafaa Mohamed Abdelghany Hassen ; Supervised Mohamed Naguib Zoheir Mostafa , Nabiel Mohsen Eldanasouri , Asmaa Ahmed Abdelaal |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
العلاقة بين التعدد الشكلى6936 أ / ج و4678 ج / س للجين الخاص بالمستقبل لبروتين سى الموجود على الخلايا المبطنة للأوعية الدموية و جلطة الأوردة العميقة |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Cairo : |
| Name of publisher, distributor, etc. |
Wafaa Mohamed Abdelghany Hassen , |
| Date of publication, distribution, etc. |
2014 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
155 P. : |
| Other physical details |
charts , facsimiles ; |
| Dimensions |
25cm |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Endothelial cell protein C receptor (EPCR) enhances the generation of activated protein C (APC) by the thrombin - thrombomodulin complex. A soluble form of EPCR (sEPCR), which is generated by metalloprotease activity, is present in plasma. Two polymorphisms in the EPCR gene (6936A / G and 4678G / C) have been reported to influence the risk of venous thromboembolism (VTE). We aimed to investigate the relation of EPCR gene polymorphisms (6936 A / G and 4678 C / G) and DVT and their relations to sEPCR in Egyptian population. This study involved 90 patients with DVT and 90 age and sex matched healthy controls. Plasma levels of soluble EPCR (sEPCR) were measured in 45 cases of the primary DVT by ELISA. PCR - RFLP was used for detection of EPCR polymorphisms (6936A / G and 4678G/C). Regarding 6936A / G, the mutant genotypes (AG, GG) was associated with increased risk for DVT (P value < 0.001, OR = 4.125, 95% CI = 2.198 - 7.740) as well as its mutant allele G (P value < 0.001, OR = 2.549, 95% CI = 1.601 - 4.061). The mutant genotypes was associated with increased levels of sEPCR P value < 0.001 |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
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| Additional physical form available note |
Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Deep venous thrombosis |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Endothelial cell protein C receptor |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Polymorphisms |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Asmaa Ahmed Abdelaal , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Mohamed Naguib Zoheir Mostafa , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Nabiel Mohsen Eldanasouri , |
| Relator term |
|
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Nazla |
| Reviser |
Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Samia |
| Reviser |
Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |
