Diagnosis of hepatocellular carcinoma using blood biomarkers / (Record no. 53521)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02457cam a2200337 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031342.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 151125s2015 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.12.02.Ph.D.2015.Ah.D |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Ahmed Abdelfattah Mohamed Attallah |
| 245 10 - TITLE STATEMENT | |
| Title | Diagnosis of hepatocellular carcinoma using blood biomarkers / |
| Statement of responsibility, etc. | Ahmed Abdelfattah Mohamed Attallah ; Supervised Sanaa O. Abdallah , Yehia M. Shaker |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تشخيص سرطان الخلايا الكبدية باستخدام دلالات حيوية فى الدم |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Ahmed Abdelfattah Mohamed Attallah , |
| Date of publication, distribution, etc. | 2015 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 146 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Science - Department of Biotechemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: simple score to discriminate HCC from patients with chronic liver diseases (CLD) is needed. The simplest score would be one that requires only variables that can be documented simply from routine laboratory tests without the need for sophisticated tests. Methods: HCC patients and liver cirrhosis (LC) patients (n=289) were enrolled in the first part of the study. Fibronectin (FN), cytokeratin-1 (CK-1), Epithelial membrane antigen (EMA) were identified in the blood using monoclonal antibodies and Western blot. Data of the estimation group 1351 patients and the validation group 2208 patients were retrospectively analyzed in the second part. Liver fibrosis as a negative control and liver cirrhosis were compared to HCC. Area under curve (AUC) was used to develop FACE score (FN+AFP+CK-1+EMA) and HCC-AFP-Routine Test (HCC-ART) score.Results: Molecular weights of FN, CK-1 and EMA were determined at 90, 67 and 130 kDa respectively in sera of patients with HCC and LC. FACE score with AUC 0.88 was obtained to discriminate HCC from LC patients. In the second part of the study we developed a much simpler & sensitive score composed of routine biomarkers in larger sample of patients |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | AFP routine test |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Blood markers |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Hepatocellular carcinoma |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sanaa O. Abdallah , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yehia M. Shaker , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Aml |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.12.02.Ph.D.2015.Ah.D | 01010110066870000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.12.02.Ph.D.2015.Ah.D | 01020110066870000 | 22.09.2023 | CD - Rom | 66870.CD |