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Effect of platelet-derived microparticles on procoagulable state in egyptian thalassemic patients / (Record no. 53720)

MARC details
000 -LEADER
fixed length control field 02779cam a2200349 a 4500
003 - CONTROL NUMBER IDENTIFIER
control field EG-GiCUC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250223031347.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 151203s2015 ua d f m 000 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency EG-GiCUC
Language of cataloging eng
Transcribing agency EG-GiCUC
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title eng
049 ## - LOCAL HOLDINGS (OCLC)
Holding library Deposite
097 ## - Thesis Degree
Thesis Level M.Sc
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
Classification number Cai01.11.28.M.Sc.2015.Mo.E
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Mohamed Abdelmohsen Abdellatif Ibraheem
245 10 - TITLE STATEMENT
Title Effect of platelet-derived microparticles on procoagulable state in egyptian thalassemic patients /
Statement of responsibility, etc. Mohamed Abdel Mohsen Abdel Latif Ibraheem ; Supervised Ilham Youssry Ibrahim , Mona Kamal Elghamrawy , Rania Mohamed Samy
246 15 - VARYING FORM OF TITLE
Title proper/short title تأثير الجزيئات الدقيقة الناتجة من الصفائح الدموية على قابلية التجلط في مرضى أنيما البحر المتوسط المصريين
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Cairo :
Name of publisher, distributor, etc. Mohamed Abdelmohsen Abdellatif Ibraheem ,
Date of publication, distribution, etc. 2015
300 ## - PHYSICAL DESCRIPTION
Extent 166 P. :
Other physical details charts ;
Dimensions 25cm
502 ## - DISSERTATION NOTE
Dissertation note Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520 ## - SUMMARY, ETC.
Summary, etc. Subjects and methods We measured platelet microparticles (MPs) in 87 thalassemia patients (39 Ý-TM, 48 Ý-TI) of any age and assessed their relation to clinicopathological characteristics. Patients were studied stressing on transfusion history, splenectomy, thrombotic events, chelation therapy, hematological and coagulation profiles, flow cytometric measurement of annexin labelled and platelet derived MPs (CD41b(+)). ResultsThalassemic patients, who experienced TEE, had significantly higher platelet count, higher annexin labelled and CD 41 labelled microparticles (p-value = 0.014, 0.003, and 0.014, respectively). Among TI and TM patients, platelet count, and CD 41 positive MPs were higher in those with TEE, but did not reach the significant values. On multiple regression analysis, older age, splenectomy, total bilirubin, CD41 and annexin labelled MPs were assessed with higher risk for TEE among thalassemia patients.Conclusion The presence of significantly higher levels of platelet-derived microparticles among thalassemia patients who experienced TEE may be an evidence of enhanced platelet activation among these patients. Platelet activation may contribute to the observed hypercoagulable state. Further studies are required to extend and confirm the pathogenesis of the observed hypercoagulable state in both TM and TI
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE
Additional physical form available note Issued also as CD
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Annexin
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term CD41
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Thalassemia
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Ilham Youssry Ibrahim ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Mona Kamal ElGhamrawy ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Rania Mohamed Samy ,
Relator term
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a>
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Enas
Reviser Cataloger
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Nazla
Reviser Revisor
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Koha item type Thesis
Holdings
Source of classification or shelving scheme Not for loan Home library Current library Date acquired Full call number Barcode Date last seen Koha item type Copy number
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة قاعة الرسائل الجامعية - الدور الاول 11.02.2024 Cai01.11.28.M.Sc.2015.Mo.E 01010110067042000 22.09.2023 Thesis  
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة مخـــزن الرســائل الجـــامعية - البدروم 11.02.2024 Cai01.11.28.M.Sc.2015.Mo.E 01020110067042000 22.09.2023 CD - Rom 67042.CD