MARC details
| 000 -LEADER |
|---|
| fixed length control field |
02710cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
151205s2015 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
EG-GiCUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GiCUC |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 049 ## - LOCAL HOLDINGS (OCLC) |
|---|
| Holding library |
Deposite |
| 097 ## - Thesis Degree |
|---|
| Thesis Level |
M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
|---|
| Classification number |
Cai01.11.27.M.Sc.2015.Ma.I |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Mai Omar Elfarouk Elsherbiny |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Immunohistochemical study of cyclin D1expression in laryngeal squamous cell carcinoma / |
| Statement of responsibility, etc. |
Mai Omar Elfarouk Elsherbiny ; Supervised Maha Mosaad Mosaad , Samar Abdelmonem Elsheikh , Maha Elsayed Salama |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
دراسة مناعية نسيجية كيميائية لتعبير سيكلين د1 فى سرطان الخلايا الحرشفية فى الحنجرة |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Cairo : |
| Name of publisher, distributor, etc. |
Mai Omar Elfarouk Elsherbiny , |
| Date of publication, distribution, etc. |
2015 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
126 P. : |
| Other physical details |
charts , facsimiles ; |
| Dimensions |
25cm |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pathology |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
The laryngeal carcinoma is the second most common head and neck squamous cell carcinoma. Cell cycle progression is facilitated by CDKs that are activated by cyclins, including Cyclin D1. Evidence of the involvement of Cyclin gene alterations and overexpression of various cyclins in human cancer is growing. The role of Cyclin D1 in malignant progression of laryngeal squamous cell carcinoma (LSCC) has yet to be established. Cyclin D1 protein was studied in 40 LSCC patients including 20 cases of Grade II, 9 cases of Grade I , 9 cases of Grade III and two cases of carcinoma insitu, retrieved as routinely processed paraffin blocks taken from the department of Pathology, Kasr El-Ainy Hospital. For all specimens, some clinical data were available on the computer files including age and sex of the patients, tumor site, tumor grading, tumor staging, infiltration of underlying cartilage and lymph node metastasis. Using Immunohistochemistry, Cyclin D1 Expressors were considered in cases exhibiting moderate or intense positive nuclear staining in {u2265} 10 of tumor cells. 23 patients (57.5 %) were considered Cyclin D1 expressors and 17 patients (42.5 %) were considered non-expressors. A significant relation was detected between Cyclin D1 expression on one hand and tumor grading, infiltration of thyroid cartilage and keratinization on one the other hand. |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
|---|
| Additional physical form available note |
Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
CDKs |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Cyclin D1 |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Laryngeal squamous cell carcinoma |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Maha Elsayed Salama , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Maha Mosaad Mosaad , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Samar Abdelmonem Elsheikh , |
| Relator term |
|
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Nazla |
| Reviser |
Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Soheir |
| Reviser |
Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |
