Molecular characterization for some single nucleotide polymorphisms in the dipeptidy1 peptidase 1 (DPPI) gene / (Record no. 53904)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 02629cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031353.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 151212s2015 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.12.02.M.Sc.2015.Gh.M |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Ghada Mohamed Abdelhaleem Elfeki |
| 245 10 - TITLE STATEMENT | |
| Title | Molecular characterization for some single nucleotide polymorphisms in the dipeptidy1 peptidase 1 (DPPI) gene / |
| Statement of responsibility, etc. | Ghada Mohamed Abdelhaleem Elfeki ; Supervised Mohamed A. Badway , Mohamed A. Eldesouky , Andrew F. Walls |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | توصيف جزيئى للطفرات أحادية القاعده النيتروجينيه الموجوده فى الجين المسئول عن انزيم تحلل ثنائى الرابطه البيبتيديه |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Ghada Mohamed Abdelhaleem Elfeki , |
| Date of publication, distribution, etc. | 2015 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 111 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Biochemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Asthma is caused by immune response to environmental stimuli, an effect in which there is airway remodelling. When individuals come in contact with stimuli, their bronchi become inflamed. The inflammatory response is triggered by a chain reaction initiated by several effector molecules. One of these molecules is cathepsin C (CTSC). A mutation within this gene could provide protection against the inflammatory response. Three hundred forty one families, each with at least two siblings with asthma were genotyped for two CTSC polymorphisms (rs217086 (T153I) AND rs3888798 (I453V)) using high resolution melting curve analysis. Genetic association analysis was analysed using family based association tests (FBAT) and resultant called genotypes were sequenced. DNA sequence data confirmed all variant genotypes. Analysis by FBAT showed no significant association between any polymorphisms and asthma susceptibility or with any of asthma-related phenotypes tested. This study failed to confirm a substantial role of the T153I and I453V, CTSC polymorphisms in the genetic predisposition for atopic asthma in a large UK family-based asthma cohort |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | DPPI |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Nucleotide |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Polymorphisms |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Andrew F. Walls , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Ahmed Badway , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Aly Eldesouky , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Soheir |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.12.02.M.Sc.2015.Gh.M | 01010110067254000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.12.02.M.Sc.2015.Gh.M | 01020110067254000 | 22.09.2023 | CD - Rom | 67254.CD |