MARC details
| 000 -LEADER |
|---|
| fixed length control field |
03706cam a2200313 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
151216s2015 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
EG-GiCUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GiCUC |
| 041 0# - LANGUAGE CODE |
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| Language code of text/sound track or separate title |
eng |
| 049 ## - LOCAL HOLDINGS (OCLC) |
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| Holding library |
Deposite |
| 097 ## - Thesis Degree |
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| Thesis Level |
M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
|---|
| Classification number |
Cai01.24.03.M.Sc.2015.Sh.P |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Shaimaa Mohamed Saber Elbasiouny |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Photodynamic diagnosis of parathyroid glands using different carriers for delivery of aminolevulinic acid / |
| Statement of responsibility, etc. |
Shaimaa Mohamed Saber Elbasiouny ; Supervised Tarek Fahmy Abdelaziz Elwakil , Maha Fadel Mohamed Ali |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
ا{uئإؤئ}{uئإ٩٧}{uئإآ٧}{uئإء٧}{uئآئإ}ص ا{uئإؤئ}{uئإآئ}و{uئإ٨آ}{uئإئ٠} ا{uئإؤئ}د {uئآئإ}{uئإإ٧}{uئإ٨إ}{uئإإ٣}{uئآئإ}{uئإؤآ}{uئإئ٠} {uئإؤئ}{uئإإ٠}{uئإؤ٠}دة ا{uئإؤئ}{uئإ٩ئ}{uئإ٨إ}ر در{uئإؤ٧}{uئآئإ}{uئآءآ} {uئإ٩١}{uئإ٨٨}{uئإآ٣}{uئإ٩٧}{uئإء٧}دام طرق {uئإإ٣}{uئإء٧}{uئإ٩٧}{uئإإ٠}{uئإؤ٤}{uئآءآ} {uئإإ٧}{uئإ٨إ}{uئإؤ٧}{uئإإ٠}{uئآءآ} {uئإؤئ}{uئإء٣}{uئإ٨إ}{uئإإ٣}ض أ{uئإإ٣}{uئآئإ}{uئإإ٧}و {uئإؤئ}{uئإؤ٤}{uئآئإ}و{uئإؤئ}{uئآئإ}{uئإإ٧}{uئآئإ}ك |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Cairo : |
| Name of publisher, distributor, etc. |
Shaimaa Mohamed Saber Elbasiouny , |
| Date of publication, distribution, etc. |
2015 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
108 P. : |
| Other physical details |
charts , facsimiles ; |
| Dimensions |
25cm |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Thesis (M.Sc.) - Cairo University - National Institute of Laser Enhanced Sciences - Department of Laser Application in Medical and Biological |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Detection of normal and pathologic parathyroid glands often is difficult due to their variability in number and location. The intraoperative identification of parathyroid glands is challenging yet very important, which is one of the main reasons for postoperative hypoparathyroidism. The feasibility and efficacy of fluorescence diagnosis using the photosensitizer aminolevulinic acid (ALA) has already been proven to identify parathyroid glands in experimental settings. Mostly, modifications of ALA aimed at improving its cellular permeability, increased stability in physiologic pH, increased selectivity and limiting side effects are important challenges in order to extend its clinical use. The present study represents ALA in delivery systems such as conventional liposomes and stealth liposomes and study the feasibility and efficacy of these forms for identifying parathyroids in a fluorescence technique and evaluates fluorescence differences between these delivery forms and the free ALA solution used before.ALA loaded conventional liposomal and stealth liposomal samples were prepared and they were characterized for drug encapsulation %, vesicle size, Zeta potential, in vitro drug release profile and thermal analysis. Seventy rats were randomized into seven groups; a peritoneal lavage was performed with either 1.5 or 3.0% ALA solution in free, conventional or stealth liposomal forms, the photosensitization times of each formula was calculated. After surgical exposure of thyroid and parathyroid glands the operative site was examined under wood{u2019}s light, the identified parathyroid glands were observed and confirmed by histological study, different forms and concentrations of ALA were compared through measuring fluorescence intensities of parathyroid glands by spectrometry |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
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| Additional physical form available note |
Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Aminolevulinic Acid |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Parathyroid Glands |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Photodynamic Diagnosis |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Maha Fadel Mohamed Ali , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Tarek Fahmy Abdelaziz Elwakil , |
| Relator term |
|
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Nazla |
| Reviser |
Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Soheir |
| Reviser |
Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |
