Association of some genetic polymorphism with diabetic nephropathy in Egyptian patients / (Record no. 54069)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02674cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031357.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 151222s2015 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.01.Ph.D.2015.We.A |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Weaam Gouda Ali Morsy |
| 245 10 - TITLE STATEMENT | |
| Title | Association of some genetic polymorphism with diabetic nephropathy in Egyptian patients / |
| Statement of responsibility, etc. | Weaam Gouda Ali Morsy ; Supervised Manal Fouad Ismail , Olfat Gamil Shaker , Esmat Ashour Wahba |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | علاقة بعض التعددات الجينيه مع الإعتلال الكلوى السكرى ندى المرضي المصريين |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Weaam Gouda Ali Morsy , |
| Date of publication, distribution, etc. | 2015 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 175 P. : |
| Other physical details | charts ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Biochemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | One of the most common complications of diabetes mellitus is diabetic nephropathy (DN). The objective of the study was to investigate the relationship between variants of angiotensin converting enzyme (ACE), transcription factor 7 - like 2 (TCF7L2) and peroxisome proliferator - activated receptor gamma coactivator - 1 alpha (PPARGC1A) gene polymorphisms individually or in combination with the development of nephropathy in type 2 diabetes mellitus (T2DM) patients. In addition, to study the relationship between variants of ACE I / D gene polymorphism, serum ACE level and the development of nephropathy in T2DM patients. Eighty five T2DM patients (Forty five with nephropathy and forty without nephropathy), and forty five healthy control subjects were included in the study. The insertion/deletion (I/D) polymorphism of ACE gene was evaluated by PCR method. The polymorphisms rs7903146 (C/T) of TCF7L2 gene and Gly482Ser (G / A) and Thr394Thr (G / A) of PPARGC1A gene were evaluated by PCR - RFLP analysis. The serum ACE level was determined using ELISA. The frequency of ACE DD genotype and D allele was significantly higher in DN patients when compared to normal controls (P = 0.001 and 0.001), respectively and diabetic patients without nephropathy (P = 0.035 and 0.004), respectively |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Angiotensin - converting enzyme (ACE) |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Diabetic nephropathy (DN) |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Type 2 diabetes mellitus (T2DM) |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Esmat Ashour Wahba , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Manal Fouad Ismail , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Olfat Gamil Shaker , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.01.Ph.D.2015.We.A | 01010110067303000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.01.Ph.D.2015.We.A | 01020110067303000 | 22.09.2023 | CD - Rom | 67303.CD |