Role of cytokines genes polymorphisms in predicting the outcome of HLA matched sibling bone marrow transplantation / (Record no. 54116)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02719cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031359.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 151226s2015 ua h f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.19.03.Ph.D.2015.Ab.R |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Abdallah Mohamed Gamil Abdallah |
| 245 10 - TITLE STATEMENT | |
| Title | Role of cytokines genes polymorphisms in predicting the outcome of HLA matched sibling bone marrow transplantation / |
| Statement of responsibility, etc. | Abdallah Mohamed Gamil Abdallah ; Supervised Azza Mahmoud Kamel , Raafat M. Abdelfattah , Gamal Thabet Ali |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | التنوع فى جينات المحركات الخلوية و دورها فى التنبؤ بنتيجة زرع النخاع بين الأشقاء المتماثلين |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Abdallah Mohamed Gamil Abdallah , |
| Date of publication, distribution, etc. | 2015 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 228 P. : |
| Other physical details | facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Clinical Pathology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Graft versus host disease (GVHD) is the major complication of allogeneic hematopoietic stem cell transplantation (HSCT) and cytokines are recognized as important mediators of GVHD. Polymorphisms in the regulatory regions of several cytokine genes have been associated with a number of immune diseases as well as post HSCT complications. The aim of this study was the detection of cytokines genes polymorphisms (CGPs) and their relation to post HSCT complications mainly GVHD in Egyptian patients receiving HSCT. The study included 106 patient/donor pairs who received peripheral blood stem cell transplantation (PBSCT) from HLA-matched identical siblings. DNA for cytokine genotyping was available for 105 patients and 98 donors only. Polymerase chain reaction with sequence specific primers (PCR-SSP) technique was used to analyze the following cytokines genotypes: Tumor necrosis factor-alpha (TNF-Ü) ({u2212}308), transforming growth factor beta1 (TGF-Ý1) (codon10 and codon 25), interleukin (IL)-6 ({u2212}174), IL-10 ({u2212}1082, {u2212}819 and {u2212}592) and Interferon {u2013}gamma (IFN-Þ) (+874). From the current study we can conclude that there was no impact of all tested CGPs on development of GVHD or other post HSCT complications. |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Allogeneic HSCT |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | GVHD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Post HSCT complications |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Azza Mahmoud Kamel , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gamal Thabet Ali , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Raafat Mohamed Abdelfattah , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Soheir |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.19.03.Ph.D.2015.Ab.R | 01010110067282000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.19.03.Ph.D.2015.Ab.R | 01020110067282000 | 22.09.2023 | CD - Rom | 67282.CD |