MARC details
000 -LEADER |
fixed length control field |
02961cam a2200325 a 4500 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
EG-GiCUC |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
160103s2015 ua h f m 000 0 eng d |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
EG-GiCUC |
Language of cataloging |
eng |
Transcribing agency |
EG-GiCUC |
041 0# - LANGUAGE CODE |
Language code of text/sound track or separate title |
eng |
049 ## - LOCAL HOLDINGS (OCLC) |
Holding library |
Deposite |
097 ## - Thesis Degree |
Thesis Level |
M.Sc |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
Classification number |
Cai01.10.13.M.Sc.2015.Ah.E |
100 0# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Ahmed Nour Eldine Abdallah |
245 10 - TITLE STATEMENT |
Title |
Evaluation of low level laser - activated adipose derived stem cells for treatment of experimental chondral defects / |
Statement of responsibility, etc. |
Ahmed Nour Eldine Abdallah ; Supervised Ashraf Aly Eldesoky Shamaa , Omar Mohammed Salah Eldin Eltookhy , Eman Mohammed Abdelmottaleb |
246 15 - VARYING FORM OF TITLE |
Title proper/short title |
تقييم الخلايا الجذعية المستخلصة من النسيج الدهنى و المحفزة بأشعة الليزر فى علاج عيوب الغضاريف المستحدثة تجريبياً |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Place of publication, distribution, etc. |
Cairo : |
Name of publisher, distributor, etc. |
Ahmed Nour Eldine Abdallah , |
Date of publication, distribution, etc. |
2015 |
300 ## - PHYSICAL DESCRIPTION |
Extent |
98 P. : |
Other physical details |
facsimiles ; |
Dimensions |
25cm |
502 ## - DISSERTATION NOTE |
Dissertation note |
Thesis (M.Sc.) - Cairo University - Faculty of Veterinary Medicine - Department of Surgery, Anesthesiology - Radiology |
520 ## - SUMMARY, ETC. |
Summary, etc. |
Regenerative therapies offer attractive alternatives for the treatment of chondral defects. Adipose - derived mesenchymal stem cells (AD - MSCs) found in the stromal vascular fraction (SVF) allow the development of one-step surgical procedure by their abundant availability and a minimal invasive technique. Low level laser irradiation (LLLI) of stem cells showed improved results on stem cell growth and proliferation. The aim of this work was to evaluate the treatment of chondral defects using single injection of laser activated SVF in a platelet rich plasma (PRP) vehicle. Chondral defects were created surgically in the femoral condoyle of 9 dogs. Autologous adipose tissue was harvested from the abdomen and SVF was isolated, added to the PRP, laser irradiated and injected intraarticularly in the right joint. The left joint was injected normal saline as control negative. Evaluation of the treatment included physical, radiological and histopathological examination. Treated joints showed marked degree of cartilage regeneration and restoration of the chondral histomorphological picture on the contrary to the control ones that showed deterioration overtime and defect filling with fibrous tissue forming a fibrocartilage at the end of 6 months period. The obtained results proved that the use of low level laser activated adipose derived stem cells is a safe, feasible technique as a single step surgical procedure and a very promising option for treatment of chondral defects |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
Additional physical form available note |
Issued also as CD |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Adipose |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Stem cells |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Stromal vascular fraction |
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Ashraf Aly Eldesoky Shamaa , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Eman Mohammed Abdelmottaleb , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Omar Mohammed Salah Eldin Eltookhy , |
Relator term |
|
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Nazla |
Reviser |
Revisor |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Samia |
Reviser |
Cataloger |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
Dewey Decimal Classification |
Koha item type |
Thesis |